BDBM50278174 CHEMBL471860::N-(2,4-dichlorobenzyl)-1-(4-fluoro-2-nitrophenylsulfonyl)piperidine-4-carboxamide

SMILES: [O-][N+](=O)c1cc(F)ccc1S(=O)(=O)N1CCC(CC1)C(=O)NCc1ccc(Cl)cc1Cl

InChI Key: InChIKey=PDMGMCAOZWRIRU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50278174   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
EBifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50278174 (CHEMBL471860 | N-(2,4-dichlorobenzyl)-1-(4-fluoro-...) Show SMILES [O-][N+](=O)c1cc(F)ccc1S(=O)(=O)N1CCC(CC1)C(=O)NCc1ccc(Cl)cc1Cl Show InChI InChI=1S/C19H18Cl2FN3O5S/c20-14-2-1-13(16(21)9-14)11-23-19(26)12-5-7-24(8-6-12)31(29,30)18-4-3-15(22)10-17(18)25(27)28/h1-4,9-10,12H,5-8,11H2,(H,23,26)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Columbia University Curated by ChEMBL					Assay Description Inhibition of epoxide hydrolase (unknown origin)				Bioorg Med Chem Lett 19: 2354-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.066 BindingDB Entry DOI: 10.7270/Q2J10322
					More data for this Ligand-Target Pair