Found 37 hits for monomerid = 50278316 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Alpha-carbonic anhydrase
(Helicobacter pylori (strain G27)) | BDBM50278316
(CHEMBL450079 | sodium pyrophosphate(V))Show InChI InChI=1S/H4O7P2/c1-8(2,3)7-9(4,5)6/h(H2,1,2,3)(H2,4,5,6)/p-4 | PDB
UniProtKB/TrEMBL
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| Article PubMed
| 6.60E+5 | -4.26 | n/a | n/a | n/a | n/a | n/a | 7.5 | 20 |
Universit£ degli Studi di Firenze
| Assay Description Inhibition of Vibrio cholerae alpha carbonic anhydrase preincubated for 15 mins by stopped-flow CO2 hydrase assay |
Bioorg Med Chem 24: 3413-7 (2016)
Article DOI: 10.1016/j.bmc.2016.05.029 BindingDB Entry DOI: 10.7270/Q2W9583B |
More data for this Ligand-Target Pair | |
α-Carbonic anhydrase (αCA)
(Helicobacter pylori) | BDBM50278316
(CHEMBL450079 | sodium pyrophosphate(V))Show InChI InChI=1S/H4O7P2/c1-8(2,3)7-9(4,5)6/h(H2,1,2,3)(H2,4,5,6)/p-4 | PDB
UniProtKB/TrEMBL
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| 6.60E+5 | -4.34 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
Università degli Studi di Firenze
| Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity Khalifah RG. The carbon dioxide hy... |
J Enzyme Inhib Med Chem 28: 388-91 (2013)
Article DOI: 10.3109/14756366.2011.649268 BindingDB Entry DOI: 10.7270/Q2S75F7K |
More data for this Ligand-Target Pair | |
Carbonic Anhydrase XIII
(Mus musculus (mouse)) | BDBM50278316
(CHEMBL450079 | sodium pyrophosphate(V))Show InChI InChI=1S/H4O7P2/c1-8(2,3)7-9(4,5)6/h(H2,1,2,3)(H2,4,5,6)/p-4 | PDB MMDB
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| 7.30E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of mouse recombinant carbonic anhydrase 13-catalyzed CO2 hydration by stopped flow assay |
Bioorg Med Chem Lett 19: 1855-7 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.088 BindingDB Entry DOI: 10.7270/Q27H1KH3 |
More data for this Ligand-Target Pair | |
β-Carbonic anhydrase (βCA)
(Helicobacter pylori) | BDBM50278316
(CHEMBL450079 | sodium pyrophosphate(V))Show InChI InChI=1S/H4O7P2/c1-8(2,3)7-9(4,5)6/h(H2,1,2,3)(H2,4,5,6)/p-4 | UniProtKB/TrEMBL
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| 7.50E+5 | -4.26 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
Università degli Studi di Firenze
| Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity Khalifah RG. The carbon dioxide hy... |
J Enzyme Inhib Med Chem 28: 388-91 (2013)
Article DOI: 10.3109/14756366.2011.649268 BindingDB Entry DOI: 10.7270/Q2S75F7K |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 7
(Homo sapiens (Human)) | BDBM50278316
(CHEMBL450079 | sodium pyrophosphate(V))Show InChI InChI=1S/H4O7P2/c1-8(2,3)7-9(4,5)6/h(H2,1,2,3)(H2,4,5,6)/p-4 | PDB MMDB
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| 8.70E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 7-catalyzed CO2 hydration by stopped flow assay |
Bioorg Med Chem Lett 19: 1855-7 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.088 BindingDB Entry DOI: 10.7270/Q27H1KH3 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 4
(Homo sapiens (Human)) | BDBM50278316
(CHEMBL450079 | sodium pyrophosphate(V))Show InChI InChI=1S/H4O7P2/c1-8(2,3)7-9(4,5)6/h(H2,1,2,3)(H2,4,5,6)/p-4 | PDB MMDB
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| 1.01E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 4-catalyzed CO2 hydration by stopped flow assay |
Bioorg Med Chem Lett 19: 1855-7 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.088 BindingDB Entry DOI: 10.7270/Q27H1KH3 |
More data for this Ligand-Target Pair | |
Alpha-carbonic anhydrase
(Vibrio cholerae) | BDBM50278316
(CHEMBL450079 | sodium pyrophosphate(V))Show InChI InChI=1S/H4O7P2/c1-8(2,3)7-9(4,5)6/h(H2,1,2,3)(H2,4,5,6)/p-4 | UniProtKB/TrEMBL
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| 2.96E+6 | -3.39 | n/a | n/a | n/a | n/a | n/a | 7.5 | 20 |
Universit£ degli Studi di Firenze
| Assay Description Inhibition of Flaveria bidentis carbonic anhydrase 1 preincubated for 15 mins by stopped-flow CO2 hydrase assay |
Bioorg Med Chem 24: 3413-7 (2016)
Article DOI: 10.1016/j.bmc.2016.05.029 BindingDB Entry DOI: 10.7270/Q2W9583B |
More data for this Ligand-Target Pair | |
Gamma-carbonic anhydrase
(Vibrio cholerae) | BDBM50278316
(CHEMBL450079 | sodium pyrophosphate(V))Show InChI InChI=1S/H4O7P2/c1-8(2,3)7-9(4,5)6/h(H2,1,2,3)(H2,4,5,6)/p-4 | UniProtKB/TrEMBL
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| 7.30E+6 | -2.86 | n/a | n/a | n/a | n/a | n/a | 7.5 | 20 |
Universit£ degli Studi di Firenze
| Assay Description Inhibition of Vibrio cholerae recombinant carbonic anhydrase gamma expressed in Escherichia coli DE3 cells preincubated for 15 mins by stopped-flow C... |
Bioorg Med Chem 24: 3413-7 (2016)
Article DOI: 10.1016/j.bmc.2016.05.029 BindingDB Entry DOI: 10.7270/Q2W9583B |
More data for this Ligand-Target Pair | |
Carbonic anhydrase
(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...) | BDBM50278316
(CHEMBL450079 | sodium pyrophosphate(V))Show InChI InChI=1S/H4O7P2/c1-8(2,3)7-9(4,5)6/h(H2,1,2,3)(H2,4,5,6)/p-4 | PDB
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| 8.20E+6 | n/a | n/a | n/a | n/a | n/a | n/a | 8.3 | n/a |
University of Florida
Curated by ChEMBL
| Assay Description Inhibition of Pseudomonas aeruginosa PAO1 type-2 beta-carbonic anhydrase psCA3 expressed in Escherichia coli Tuner BL21 (DE3) cells pre-incubated for... |
Bioorg Med Chem 23: 4831-8 (2015)
BindingDB Entry DOI: 10.7270/Q20V8FK8 |
More data for this Ligand-Target Pair | |
Beta-carbonic anhydrase
(Vibrio cholerae) | BDBM50278316
(CHEMBL450079 | sodium pyrophosphate(V))Show InChI InChI=1S/H4O7P2/c1-8(2,3)7-9(4,5)6/h(H2,1,2,3)(H2,4,5,6)/p-4 | PDB
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| 1.51E+7 | -2.44 | n/a | n/a | n/a | n/a | n/a | 7.5 | 20 |
Universit£ degli Studi di Firenze
| Assay Description Inhibition of Vibrio cholerae carbonic anhydrase beta preincubated for 15 mins by stopped-flow CO2 hydrase assay |
Bioorg Med Chem 24: 3413-7 (2016)
Article DOI: 10.1016/j.bmc.2016.05.029 BindingDB Entry DOI: 10.7270/Q2W9583B |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50278316
(CHEMBL450079 | sodium pyrophosphate(V))Show InChI InChI=1S/H4O7P2/c1-8(2,3)7-9(4,5)6/h(H2,1,2,3)(H2,4,5,6)/p-4 | PDB MMDB
NCI pathway Reactome pathway KEGG
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| Article PubMed
| 2.58E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto di Bioscienze e Biorisorse (IBBR)-CNR
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration method |
Bioorg Med Chem Lett 24: 4389-96 (2014)
Article DOI: 10.1016/j.bmcl.2014.08.015 BindingDB Entry DOI: 10.7270/Q28054D1 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50278316
(CHEMBL450079 | sodium pyrophosphate(V))Show InChI InChI=1S/H4O7P2/c1-8(2,3)7-9(4,5)6/h(H2,1,2,3)(H2,4,5,6)/p-4 | PDB MMDB
NCI pathway Reactome pathway KEGG
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| Article PubMed
| 2.58E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Slovak Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 1 by stopped flow CO2 hydration assay |
Bioorg Med Chem Lett 22: 1314-6 (2012)
Article DOI: 10.1016/j.bmcl.2011.12.085 BindingDB Entry DOI: 10.7270/Q2W66M7M |
More data for this Ligand-Target Pair | |
Carbonic anhydrase
(Homo sapiens (Human)) | BDBM50278316
(CHEMBL450079 | sodium pyrophosphate(V))Show InChI InChI=1S/H4O7P2/c1-8(2,3)7-9(4,5)6/h(H2,1,2,3)(H2,4,5,6)/p-4 | PDB MMDB
NCI pathway Reactome pathway KEGG
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| 2.58E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tampere and Tampere University Hospital
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase-1 at 20 degC preincubated for 15 mins by stopped-flow CO2 hydrase assay |
Bioorg Med Chem 21: 4472-6 (2013)
Article DOI: 10.1016/j.bmc.2013.05.058 BindingDB Entry DOI: 10.7270/Q28S4SV8 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50278316
(CHEMBL450079 | sodium pyrophosphate(V))Show InChI InChI=1S/H4O7P2/c1-8(2,3)7-9(4,5)6/h(H2,1,2,3)(H2,4,5,6)/p-4 | PDB MMDB
NCI pathway Reactome pathway KEGG
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| Article PubMed
| 2.58E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human cytosolic carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assay |
Bioorg Med Chem Lett 22: 7142-5 (2012)
Article DOI: 10.1016/j.bmcl.2012.09.065 BindingDB Entry DOI: 10.7270/Q2930VB8 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50278316
(CHEMBL450079 | sodium pyrophosphate(V))Show InChI InChI=1S/H4O7P2/c1-8(2,3)7-9(4,5)6/h(H2,1,2,3)(H2,4,5,6)/p-4 | PDB MMDB
NCI pathway Reactome pathway KEGG
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| Article PubMed
| 2.58E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 1-catalyzed CO2 hydration by stopped flow assay |
Bioorg Med Chem Lett 19: 1855-7 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.088 BindingDB Entry DOI: 10.7270/Q27H1KH3 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50278316
(CHEMBL450079 | sodium pyrophosphate(V))Show InChI InChI=1S/H4O7P2/c1-8(2,3)7-9(4,5)6/h(H2,1,2,3)(H2,4,5,6)/p-4 | PDB MMDB
NCI pathway Reactome pathway KEGG
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| Article PubMed
| 2.58E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assay |
Bioorg Med Chem Lett 23: 1636-8 (2013)
Article DOI: 10.1016/j.bmcl.2013.01.084 BindingDB Entry DOI: 10.7270/Q2VD70TX |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50278316
(CHEMBL450079 | sodium pyrophosphate(V))Show InChI InChI=1S/H4O7P2/c1-8(2,3)7-9(4,5)6/h(H2,1,2,3)(H2,4,5,6)/p-4 | PDB MMDB
NCI pathway Reactome pathway KEGG
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| Article PubMed
| 2.58E+7 | n/a | n/a | n/a | n/a | n/a | n/a | 8.3 | n/a |
Universit£ degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of recombinant human carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay at pH 8.3 |
Bioorg Med Chem Lett 21: 3591-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.04.105 BindingDB Entry DOI: 10.7270/Q2930TGN |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50278316
(CHEMBL450079 | sodium pyrophosphate(V))Show InChI InChI=1S/H4O7P2/c1-8(2,3)7-9(4,5)6/h(H2,1,2,3)(H2,4,5,6)/p-4 | PDB MMDB
NCI pathway Reactome pathway KEGG
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| Article PubMed
| 2.58E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay |
Bioorg Med Chem 19: 243-8 (2011)
Article DOI: 10.1016/j.bmc.2010.11.031 BindingDB Entry DOI: 10.7270/Q2B858D2 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50278316
(CHEMBL450079 | sodium pyrophosphate(V))Show InChI InChI=1S/H4O7P2/c1-8(2,3)7-9(4,5)6/h(H2,1,2,3)(H2,4,5,6)/p-4 | PDB MMDB
NCI pathway Reactome pathway KEGG
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| Article PubMed
| 2.58E+7 | -2.13 | n/a | n/a | n/a | n/a | n/a | 7.5 | 20 |
Universit£ degli Studi di Firenze
| Assay Description Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped-flow CO2 hydrase assay |
Bioorg Med Chem 24: 3413-7 (2016)
Article DOI: 10.1016/j.bmc.2016.05.029 BindingDB Entry DOI: 10.7270/Q2W9583B |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50278316
(CHEMBL450079 | sodium pyrophosphate(V))Show InChI InChI=1S/H4O7P2/c1-8(2,3)7-9(4,5)6/h(H2,1,2,3)(H2,4,5,6)/p-4 | PDB MMDB
Reactome pathway KEGG
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| Article PubMed
| 4.85E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration method |
Bioorg Med Chem Lett 24: 4402-6 (2014)
Article DOI: 10.1016/j.bmcl.2014.08.014 BindingDB Entry DOI: 10.7270/Q2348N4M |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50278316
(CHEMBL450079 | sodium pyrophosphate(V))Show InChI InChI=1S/H4O7P2/c1-8(2,3)7-9(4,5)6/h(H2,1,2,3)(H2,4,5,6)/p-4 | PDB MMDB
Reactome pathway KEGG
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| Article PubMed
| 4.85E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Slovak Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 2 by stopped flow CO2 hydration assay |
Bioorg Med Chem Lett 22: 1314-6 (2012)
Article DOI: 10.1016/j.bmcl.2011.12.085 BindingDB Entry DOI: 10.7270/Q2W66M7M |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50278316
(CHEMBL450079 | sodium pyrophosphate(V))Show InChI InChI=1S/H4O7P2/c1-8(2,3)7-9(4,5)6/h(H2,1,2,3)(H2,4,5,6)/p-4 | PDB MMDB
Reactome pathway KEGG
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| Article PubMed
| 4.85E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto di Bioscienze e Biorisorse (IBBR)-CNR
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration method |
Bioorg Med Chem Lett 24: 4389-96 (2014)
Article DOI: 10.1016/j.bmcl.2014.08.015 BindingDB Entry DOI: 10.7270/Q28054D1 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50278316
(CHEMBL450079 | sodium pyrophosphate(V))Show InChI InChI=1S/H4O7P2/c1-8(2,3)7-9(4,5)6/h(H2,1,2,3)(H2,4,5,6)/p-4 | PDB MMDB
Reactome pathway KEGG
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Similars
| Article PubMed
| 4.85E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto di Biostrutture e Bioimmagini
Curated by ChEMBL
| Assay Description Inhibition of human cytosolic carbonic anhydrase-2 preincubated for 15 mins by stopped flow CO2 hydration assay |
Bioorg Med Chem Lett 23: 1626-30 (2013)
Article DOI: 10.1016/j.bmcl.2013.01.087 BindingDB Entry DOI: 10.7270/Q23X8806 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50278316
(CHEMBL450079 | sodium pyrophosphate(V))Show InChI InChI=1S/H4O7P2/c1-8(2,3)7-9(4,5)6/h(H2,1,2,3)(H2,4,5,6)/p-4 | PDB MMDB
Reactome pathway KEGG
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Similars
| PubMed
| 4.85E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto di Bioscienze e Biorisorse, CNR
Curated by ChEMBL
| Assay Description Inhibition of recombinant human carbonic anhydrase 2 assessed as inhibition of CO2 hydration incubated for 15 mins prior to testing by stopped flow C... |
Bioorg Med Chem 25: 2010-2015 (2017)
BindingDB Entry DOI: 10.7270/Q2JD5012 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50278316
(CHEMBL450079 | sodium pyrophosphate(V))Show InChI InChI=1S/H4O7P2/c1-8(2,3)7-9(4,5)6/h(H2,1,2,3)(H2,4,5,6)/p-4 | PDB MMDB
Reactome pathway KEGG
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Similars
| Article PubMed
| 4.85E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assay |
Bioorg Med Chem Lett 23: 1636-8 (2013)
Article DOI: 10.1016/j.bmcl.2013.01.084 BindingDB Entry DOI: 10.7270/Q2VD70TX |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50278316
(CHEMBL450079 | sodium pyrophosphate(V))Show InChI InChI=1S/H4O7P2/c1-8(2,3)7-9(4,5)6/h(H2,1,2,3)(H2,4,5,6)/p-4 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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Similars
| Article PubMed
| 4.85E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto di Bioscienze e Biorisorse
Curated by ChEMBL
| Assay Description Inhibition of human CA2 after 15 mins by stopped-flow/Co2 hydration assay |
Bioorg Med Chem 23: 4405-9 (2015)
Article DOI: 10.1016/j.bmc.2015.06.021 BindingDB Entry DOI: 10.7270/Q2JD4ZJ0 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50278316
(CHEMBL450079 | sodium pyrophosphate(V))Show InChI InChI=1S/H4O7P2/c1-8(2,3)7-9(4,5)6/h(H2,1,2,3)(H2,4,5,6)/p-4 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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Similars
| Article PubMed
| 4.85E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CNR
Curated by ChEMBL
| Assay Description Inhibition of human CA2 incubated for 15 mins by stopped-flow CO2 hydration assay |
Bioorg Med Chem 25: 4800-4804 (2017)
Article DOI: 10.1016/j.bmc.2017.07.033 BindingDB Entry DOI: 10.7270/Q2028V0P |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50278316
(CHEMBL450079 | sodium pyrophosphate(V))Show InChI InChI=1S/H4O7P2/c1-8(2,3)7-9(4,5)6/h(H2,1,2,3)(H2,4,5,6)/p-4 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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Similars
| Article PubMed
| 4.85E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 2-catalyzed CO2 hydration by stopped flow assay |
Bioorg Med Chem Lett 19: 1855-7 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.088 BindingDB Entry DOI: 10.7270/Q27H1KH3 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50278316
(CHEMBL450079 | sodium pyrophosphate(V))Show InChI InChI=1S/H4O7P2/c1-8(2,3)7-9(4,5)6/h(H2,1,2,3)(H2,4,5,6)/p-4 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
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Similars
| Article PubMed
| 4.85E+7 | -1.76 | n/a | n/a | n/a | n/a | n/a | 7.5 | 20 |
Universit£ degli Studi di Firenze
| Assay Description Inhibition of Helicobacter pylori alpha carbonic anhydrase preincubated for 15 mins by stopped-flow CO2 hydrase assay |
Bioorg Med Chem 24: 3413-7 (2016)
Article DOI: 10.1016/j.bmc.2016.05.029 BindingDB Entry DOI: 10.7270/Q2W9583B |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50278316
(CHEMBL450079 | sodium pyrophosphate(V))Show InChI InChI=1S/H4O7P2/c1-8(2,3)7-9(4,5)6/h(H2,1,2,3)(H2,4,5,6)/p-4 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem
Similars
| Article PubMed
| 4.85E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human cytosolic carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assay |
Bioorg Med Chem Lett 22: 7142-5 (2012)
Article DOI: 10.1016/j.bmcl.2012.09.065 BindingDB Entry DOI: 10.7270/Q2930VB8 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50278316
(CHEMBL450079 | sodium pyrophosphate(V))Show InChI InChI=1S/H4O7P2/c1-8(2,3)7-9(4,5)6/h(H2,1,2,3)(H2,4,5,6)/p-4 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem
Similars
| Article PubMed
| 4.85E+7 | n/a | n/a | n/a | n/a | n/a | n/a | 8.3 | n/a |
Universit£ degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of recombinant human carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assay at pH 8.3 |
Bioorg Med Chem Lett 21: 3591-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.04.105 BindingDB Entry DOI: 10.7270/Q2930TGN |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50278316
(CHEMBL450079 | sodium pyrophosphate(V))Show InChI InChI=1S/H4O7P2/c1-8(2,3)7-9(4,5)6/h(H2,1,2,3)(H2,4,5,6)/p-4 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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Similars
| Article PubMed
| 4.85E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Italy; Universit£ degliStudi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 2 assessed as inhibition of CO2 hydration preincubated for 15 mins by Lineweaver-burk plot method |
Bioorg Med Chem 25: 575-580 (2017)
Article DOI: 10.1016/j.bmc.2016.11.021 BindingDB Entry DOI: 10.7270/Q2M047FF |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50278316
(CHEMBL450079 | sodium pyrophosphate(V))Show InChI InChI=1S/H4O7P2/c1-8(2,3)7-9(4,5)6/h(H2,1,2,3)(H2,4,5,6)/p-4 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem
Similars
| Article PubMed
| 4.85E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assay |
Bioorg Med Chem 19: 243-8 (2011)
Article DOI: 10.1016/j.bmc.2010.11.031 BindingDB Entry DOI: 10.7270/Q2B858D2 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50278316
(CHEMBL450079 | sodium pyrophosphate(V))Show InChI InChI=1S/H4O7P2/c1-8(2,3)7-9(4,5)6/h(H2,1,2,3)(H2,4,5,6)/p-4 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem
Similars
| Article PubMed
| 4.85E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kochi Medical School
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 2 by stopped-flow CO2 hydrase assay |
Bioorg Med Chem Lett 24: 1127-32 (2014)
Article DOI: 10.1016/j.bmcl.2013.12.124 BindingDB Entry DOI: 10.7270/Q2FX7DDZ |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50278316
(CHEMBL450079 | sodium pyrophosphate(V))Show InChI InChI=1S/H4O7P2/c1-8(2,3)7-9(4,5)6/h(H2,1,2,3)(H2,4,5,6)/p-4 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem
Similars
| PubMed
| 4.85E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description Inhibition of Pseudomonas aeruginosa PAO1 type-2 beta-carbonic anhydrase psCA3 expressed in Escherichia coli Tuner BL21 (DE3) cells pre-incubated for... |
Bioorg Med Chem 23: 4831-8 (2015)
BindingDB Entry DOI: 10.7270/Q20V8FK8 |
More data for this Ligand-Target Pair | |
Astrosclerin-3
(Astrosclera willeyana) | BDBM50278316
(CHEMBL450079 | sodium pyrophosphate(V))Show InChI InChI=1S/H4O7P2/c1-8(2,3)7-9(4,5)6/h(H2,1,2,3)(H2,4,5,6)/p-4 | UniProtKB/TrEMBL
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Similars
| Article PubMed
| 5.77E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Slovak Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibition of Astrosclera willeyana recombinant GST-tagged astrosclerin 3 expressed in Escherichia coli BL21-DE3-RIPL cells preincubated for 15 mins ... |
Bioorg Med Chem Lett 22: 1314-6 (2012)
Article DOI: 10.1016/j.bmcl.2011.12.085 BindingDB Entry DOI: 10.7270/Q2W66M7M |
More data for this Ligand-Target Pair | |
Butyrophilin subfamily 3 member A1
(Homo sapiens (Human)) | BDBM50278316
(CHEMBL450079 | sodium pyrophosphate(V))Show InChI InChI=1S/H4O7P2/c1-8(2,3)7-9(4,5)6/h(H2,1,2,3)(H2,4,5,6)/p-4 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
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Similars
| Article PubMed
| n/a | n/a | 1.14E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Western Michigan University
Curated by ChEMBL
| Assay Description Displacement of GDP-BODIPY from C-terminal 6His-tagged BTN3A1 B30.2 domain (unknown origin) expressed in Escherichia coli BL21 (DE) measured after 60... |
J Med Chem 62: 6814-6823 (2019)
Article DOI: 10.1021/acs.jmedchem.9b00825 |
More data for this Ligand-Target Pair | |