BDBM50278478 (R)-N-ethyl-N-(pyrrolidin-3-yl)naphthalene-2-sulfonamide::CHEMBL446230

SMILES: CCN([C@@H]1CCNC1)S(=O)(=O)c1ccc2ccccc2c1

InChI Key: InChIKey=PEOZAOHZZSCNEV-OAHLLOKOSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50278478   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50278478 ((R)-N-ethyl-N-(pyrrolidin-3-yl)naphthalene-2-sulfo...) Show SMILES CCN([C@@H]1CCNC1)S(=O)(=O)c1ccc2ccccc2c1 |r| Show InChI InChI=1S/C16H20N2O2S/c1-2-18(15-9-10-17-12-15)21(19,20)16-8-7-13-5-3-4-6-14(13)11-16/h3-8,11,15,17H,2,9-10,12H2,1H3/t15-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of radiolabeled serotonin reuptake at human SERT expressed in HEK293 cells				Bioorg Med Chem Lett 19: 2329-32 (2009) Article DOI: 10.1016/j.bmcl.2009.02.054 BindingDB Entry DOI: 10.7270/Q2251J39
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50278478 ((R)-N-ethyl-N-(pyrrolidin-3-yl)naphthalene-2-sulfo...) Show SMILES CCN([C@@H]1CCNC1)S(=O)(=O)c1ccc2ccccc2c1 |r| Show InChI InChI=1S/C16H20N2O2S/c1-2-18(15-9-10-17-12-15)21(19,20)16-8-7-13-5-3-4-6-14(13)11-16/h3-8,11,15,17H,2,9-10,12H2,1H3/t15-/m1/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of radiolabeled dopamine reuptake at human DAT expressed in HEK293 cells				Bioorg Med Chem Lett 19: 2329-32 (2009) Article DOI: 10.1016/j.bmcl.2009.02.054 BindingDB Entry DOI: 10.7270/Q2251J39
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50278478 ((R)-N-ethyl-N-(pyrrolidin-3-yl)naphthalene-2-sulfo...) Show SMILES CCN([C@@H]1CCNC1)S(=O)(=O)c1ccc2ccccc2c1 |r| Show InChI InChI=1S/C16H20N2O2S/c1-2-18(15-9-10-17-12-15)21(19,20)16-8-7-13-5-3-4-6-14(13)11-16/h3-8,11,15,17H,2,9-10,12H2,1H3/t15-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of radiolabeled noradrenaline reuptake at human NET expressed in HEK293 cells				Bioorg Med Chem Lett 19: 2329-32 (2009) Article DOI: 10.1016/j.bmcl.2009.02.054 BindingDB Entry DOI: 10.7270/Q2251J39
					More data for this Ligand-Target Pair