BDBM50278481 (R)-N-methyl-N-(naphthalen-2-ylmethyl)pyrrolidin-3-amine::CHEMBL469607

SMILES: CN(Cc1ccc2ccccc2c1)[C@@H]1CCNC1

InChI Key: InChIKey=MLXZSGRSLJXYNT-MRXNPFEDSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50278481   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50278481 ((R)-N-methyl-N-(naphthalen-2-ylmethyl)pyrrolidin-3...) Show SMILES CN(Cc1ccc2ccccc2c1)[C@@H]1CCNC1 |r| Show InChI InChI=1S/C16H20N2/c1-18(16-8-9-17-11-16)12-13-6-7-14-4-2-3-5-15(14)10-13/h2-7,10,16-17H,8-9,11-12H2,1H3/t16-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	119	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of radiolabeled serotonin reuptake at human SERT expressed in HEK293 cells				Bioorg Med Chem Lett 19: 2329-32 (2009) Article DOI: 10.1016/j.bmcl.2009.02.054 BindingDB Entry DOI: 10.7270/Q2251J39
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50278481 ((R)-N-methyl-N-(naphthalen-2-ylmethyl)pyrrolidin-3...) Show SMILES CN(Cc1ccc2ccccc2c1)[C@@H]1CCNC1 |r| Show InChI InChI=1S/C16H20N2/c1-18(16-8-9-17-11-16)12-13-6-7-14-4-2-3-5-15(14)10-13/h2-7,10,16-17H,8-9,11-12H2,1H3/t16-/m1/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of radiolabeled dopamine reuptake at human DAT expressed in HEK293 cells				Bioorg Med Chem Lett 19: 2329-32 (2009) Article DOI: 10.1016/j.bmcl.2009.02.054 BindingDB Entry DOI: 10.7270/Q2251J39
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50278481 ((R)-N-methyl-N-(naphthalen-2-ylmethyl)pyrrolidin-3...) Show SMILES CN(Cc1ccc2ccccc2c1)[C@@H]1CCNC1 |r| Show InChI InChI=1S/C16H20N2/c1-18(16-8-9-17-11-16)12-13-6-7-14-4-2-3-5-15(14)10-13/h2-7,10,16-17H,8-9,11-12H2,1H3/t16-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of radiolabeled noradrenaline reuptake at human NET expressed in HEK293 cells				Bioorg Med Chem Lett 19: 2329-32 (2009) Article DOI: 10.1016/j.bmcl.2009.02.054 BindingDB Entry DOI: 10.7270/Q2251J39
					More data for this Ligand-Target Pair