BDBM50278636 4-(2-chlorobenzylidene)-1-(3,4-dichlorophenyl)pyrazolidine-3,5-dione::CHEMBL469346

SMILES: Clc1ccc(cc1Cl)N1NC(=O)C(=Cc2ccccc2Cl)C1=O

InChI Key: InChIKey=ZPDTXZWNEOBTJE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50278636   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual-specificity tyrosine-phosphorylation regulated kinase 1A (Homo sapiens (Human))	BDBM50278636 (4-(2-chlorobenzylidene)-1-(3,4-dichlorophenyl)pyra...) Show SMILES Clc1ccc(cc1Cl)N1NC(=O)C(=Cc2ccccc2Cl)C1=O |w:13.14| Show InChI InChI=1S/C16H9Cl3N2O2/c17-12-4-2-1-3-9(12)7-11-15(22)20-21(16(11)23)10-5-6-13(18)14(19)8-10/h1-8H,(H,20,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Inje University Curated by ChEMBL					Assay Description Inhibition of Dyrk1 (unknown origin) autophosphorylation				Bioorg Med Chem Lett 19: 2324-8 (2009) Article DOI: 10.1016/j.bmcl.2009.02.062 BindingDB Entry DOI: 10.7270/Q2SN08VT
					More data for this Ligand-Target Pair