BDBM50278664 CHEMBL4168260

SMILES: CC(C)n1ncnc1-c1cn2CCOc3ccc(CN4CCC(CC4)C(C)(C)O)cc3-c2n1

InChI Key: InChIKey=HELJVHJYMYFCBN-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50278664   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50278664 (CHEMBL4168260) Show SMILES CC(C)n1ncnc1-c1cn2CCOc3ccc(CN4CCC(CC4)C(C)(C)O)cc3-c2n1 Show InChI InChI=1S/C25H34N6O2/c1-17(2)31-24(26-16-27-31)21-15-30-11-12-33-22-6-5-18(13-20(22)23(30)28-21)14-29-9-7-19(8-10-29)25(3,4)32/h5-6,13,15-17,19,32H,7-12,14H2,1-4H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Binding affinity to PI3Kdelta (unknown origin)				ACS Med Chem Lett 8: 936-940 (2017) Article DOI: 10.1021/acsmedchemlett.7b00170 BindingDB Entry DOI: 10.7270/Q2CV4M7R
					More data for this Ligand-Target Pair