BDBM50278667 CHEMBL4167171

SMILES: CC(C)n1ncnc1-c1cn2CCOc3ccc(cc3-c2n1)S(=O)(=O)N1CCN(CC1)C(C)(C)C

InChI Key: InChIKey=VNFMBTATHSIRPB-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50278667   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50278667 (CHEMBL4167171) Show SMILES CC(C)n1ncnc1-c1cn2CCOc3ccc(cc3-c2n1)S(=O)(=O)N1CCN(CC1)C(C)(C)C Show InChI InChI=1S/C24H33N7O3S/c1-17(2)31-23(25-16-26-31)20-15-28-12-13-34-21-7-6-18(14-19(21)22(28)27-20)35(32,33)30-10-8-29(9-11-30)24(3,4)5/h6-7,14-17H,8-13H2,1-5H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Binding affinity to PI3Kdelta (unknown origin)				ACS Med Chem Lett 8: 936-940 (2017) Article DOI: 10.1021/acsmedchemlett.7b00170 BindingDB Entry DOI: 10.7270/Q2CV4M7R
					More data for this Ligand-Target Pair