BDBM50278751 CHEMBL4159115

SMILES: COc1nc(Br)cnc1NS(=O)(=O)c1ccc(Cl)cc1Cl

InChI Key: InChIKey=PCUSGNBFVWJYOM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50278751   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50278751 (CHEMBL4159115) Show SMILES COc1nc(Br)cnc1NS(=O)(=O)c1ccc(Cl)cc1Cl Show InChI InChI=1S/C11H8BrCl2N3O3S/c1-20-11-10(15-5-9(12)16-11)17-21(18,19)8-3-2-6(13)4-7(8)14/h2-5H,1H3,(H,15,17)	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	126	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Antagonist activity at recombinant human CCR4 expressed in CHO-K1 cells assessed as inhibition of CCL22 induced Ca2+ mobilization after 2 hrs by FMAT...				ACS Med Chem Lett 8: 981-986 (2017) Article DOI: 10.1021/acsmedchemlett.7b00315 BindingDB Entry DOI: 10.7270/Q2KD21DK
					More data for this Ligand-Target Pair