BDBM50278765 CHEMBL4176859

SMILES: COc1nc(Br)cnc1NS(=O)(=O)c1ccc(Cl)cc1

InChI Key: InChIKey=XOJBRGMLSMEWQQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50278765   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50278765 (CHEMBL4176859) Show SMILES COc1nc(Br)cnc1NS(=O)(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C11H9BrClN3O3S/c1-19-11-10(14-6-9(12)15-11)16-20(17,18)8-4-2-7(13)3-5-8/h2-6H,1H3,(H,14,16)	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	126	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Antagonist activity at recombinant human CCR4 expressed in CHO-K1 cells assessed as inhibition of CCL22 induced Ca2+ mobilization after 2 hrs by FMAT...				ACS Med Chem Lett 8: 981-986 (2017) Article DOI: 10.1021/acsmedchemlett.7b00315 BindingDB Entry DOI: 10.7270/Q2KD21DK
					More data for this Ligand-Target Pair