BDBM50279261 CHEMBL4166504

SMILES: CC(C)OC(=O)N(CCc1ccccc1)Cc1ccc(cc1)C(=O)NO

InChI Key: InChIKey=VWQSWQYFIGQEHR-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50279261   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50279261 (CHEMBL4166504) Show SMILES CC(C)OC(=O)N(CCc1ccccc1)Cc1ccc(cc1)C(=O)NO Show InChI InChI=1S/C20H24N2O4/c1-15(2)26-20(24)22(13-12-16-6-4-3-5-7-16)14-17-8-10-18(11-9-17)19(23)21-25/h3-11,15,25H,12-14H2,1-2H3,(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.74E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of recombinant human full length HDAC1 expressed in baculovirus infected Sf9 insect cells using p53 (379 to 382 residues) derived RHKKAc a...				ACS Med Chem Lett 8: 1031-1036 (2017) Article DOI: 10.1021/acsmedchemlett.7b00223 BindingDB Entry DOI: 10.7270/Q2280B3G
					More data for this Ligand-Target Pair
Cereblon/Histone deacetylase 6 (Homo sapiens (Human))	BDBM50279261 (CHEMBL4166504) Show SMILES CC(C)OC(=O)N(CCc1ccccc1)Cc1ccc(cc1)C(=O)NO Show InChI InChI=1S/C20H24N2O4/c1-15(2)26-20(24)22(13-12-16-6-4-3-5-7-16)14-17-8-10-18(11-9-17)19(23)21-25/h3-11,15,25H,12-14H2,1-2H3,(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of recombinant human full length HDAC6 expressed in baculovirus infected Sf9 insect cells using p53 (379 to 382 residues) derived RHKKAc a...				ACS Med Chem Lett 8: 1031-1036 (2017) Article DOI: 10.1021/acsmedchemlett.7b00223 BindingDB Entry DOI: 10.7270/Q2280B3G
					More data for this Ligand-Target Pair