BDBM50279583 CHEMBL505581::N-[(1S,2S,4R,5R)-5-Guanidino-2,4-bis-(4-guanidino-naphthalen-1-yloxy)-cyclohexyl]-guanidine

SMILES: [#7]\[#6](-[#7])=[#7]\[#6@@H]-1-[#6]-[#6@H](\[#7]=[#6](\[#7])-[#7])-[#6@H](-[#6]-[#6@H]1-[#8]-c1ccc(\[#7]=[#6](\[#7])-[#7])c2ccccc12)-[#8]-c1ccc(\[#7]=[#6](\[#7])-[#7])c2ccccc12

InChI Key: InChIKey=LTXPGDDRGDRKKV-MNHALERFSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50279583   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Homo sapiens furin (paired basic amino acid cleaving enzyme) (FURIN), mRNA (Homo sapiens (Human))	BDBM50279583 (CHEMBL505581 | N-[(1S,2S,4R,5R)-5-Guanidino-2,4-bi...) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6@@H]-1-[#6]-[#6@H](\[#7]=[#6](\[#7])-[#7])-[#6@H](-[#6]-[#6@H]1-[#8]-c1ccc(\[#7]=[#6](\[#7])-[#7])c2ccccc12)-[#8]-c1ccc(\[#7]=[#6](\[#7])-[#7])c2ccccc12 |r| Show InChI InChI=1S/C30H36N12O2/c31-27(32)39-19-9-11-23(17-7-3-1-5-15(17)19)43-25-14-26(22(42-30(37)38)13-21(25)41-29(35)36)44-24-12-10-20(40-28(33)34)16-6-2-4-8-18(16)24/h1-12,21-22,25-26H,13-14H2,(H4,31,32,39)(H4,33,34,40)(H4,35,36,41)(H4,37,38,42)/t21-,22+,25-,26+	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	69	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mahidol University Curated by ChEMBL					Assay Description Inhibition of human recombinant furin-dependent anthrax protective antigen processing				Eur J Med Chem 44: 1664-73 (2009) Article DOI: 10.1016/j.ejmech.2008.09.028 BindingDB Entry DOI: 10.7270/Q2MK6CQ9
					More data for this Ligand-Target Pair