BDBM50279606 1-[(1R,2R,4S,5S)-2,4-bis(4-carbamimidamidophenoxy)-5-[(4-carbamimidamidophenyl)amino]cyclohexyl]guanidine::CHEMBL506022

SMILES: [#7]\[#6](-[#7])=[#7]\[#6@@H]-1-[#6]-[#6@H](-[#7]-c2ccc(cc2)\[#7]=[#6](\[#7])-[#7])-[#6@H](-[#6]-[#6@H]1-[#8]-c1ccc(cc1)\[#7]=[#6](\[#7])-[#7])-[#8]-c1ccc(cc1)\[#7]=[#6](\[#7])-[#7]

InChI Key: InChIKey=PKMXMBXOZUEHDV-UARRHKHWSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50279606   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Homo sapiens furin (paired basic amino acid cleaving enzyme) (FURIN), mRNA (Homo sapiens (Human))	BDBM50279606 (1-[(1R,2R,4S,5S)-2,4-bis(4-carbamimidamidophenoxy)...) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6@@H]-1-[#6]-[#6@H](-[#7]-c2ccc(cc2)\[#7]=[#6](\[#7])-[#7])-[#6@H](-[#6]-[#6@H]1-[#8]-c1ccc(cc1)\[#7]=[#6](\[#7])-[#7])-[#8]-c1ccc(cc1)\[#7]=[#6](\[#7])-[#7] |r| Show InChI InChI=1S/C28H37N13O2/c29-25(30)38-16-3-1-15(2-4-16)37-21-13-22(41-28(35)36)24(43-20-11-7-18(8-12-20)40-27(33)34)14-23(21)42-19-9-5-17(6-10-19)39-26(31)32/h1-12,21-24,37H,13-14H2,(H4,29,30,38)(H4,31,32,39)(H4,33,34,40)(H4,35,36,41)/t21-,22+,23-,24+/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	46	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mahidol University Curated by ChEMBL					Assay Description Inhibition of human recombinant furin-dependent anthrax protective antigen processing				Eur J Med Chem 44: 1664-73 (2009) Article DOI: 10.1016/j.ejmech.2008.09.028 BindingDB Entry DOI: 10.7270/Q2MK6CQ9
					More data for this Ligand-Target Pair