BDBM50279847 10H-Phenoxazine-1-carboxylic acid methyl ester::CHEMBL274541

SMILES: COC(=O)c1cccc2Oc3ccccc3Nc12

InChI Key: InChIKey=DPNDVPDLIPHHBV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50279847   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Homo sapiens (Human))	BDBM50279847 (10H-Phenoxazine-1-carboxylic acid methyl ester | C...) Show SMILES COC(=O)c1cccc2Oc3ccccc3Nc12 Show InChI InChI=1S/C14H11NO3/c1-17-14(16)9-5-4-8-12-13(9)15-10-6-2-3-7-11(10)18-12/h2-8,15H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	770	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of [14C]-arachidonic acid conversion to 5-HETE by broken cell 5-lipoxygenase in vitro (guinea pig PMN)				Bioorg Med Chem Lett 1: 107-110 (1991) Article DOI: 10.1016/S0960-894X(00)80241-3 BindingDB Entry DOI: 10.7270/Q2DF6R3J
					More data for this Ligand-Target Pair