BDBM50279854 (E)-3-(10H-Phenoxazin-2-yl)-acrylic acid::CHEMBL273438

SMILES: OC(=O)\C=C\c1ccc2Oc3ccccc3Nc2c1

InChI Key: InChIKey=WGPONINAPGQVDM-SOFGYWHQSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50279854   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Homo sapiens (Human))	BDBM50279854 ((E)-3-(10H-Phenoxazin-2-yl)-acrylic acid | CHEMBL2...) Show SMILES OC(=O)\C=C\c1ccc2Oc3ccccc3Nc2c1 Show InChI InChI=1S/C15H11NO3/c17-15(18)8-6-10-5-7-14-12(9-10)16-11-3-1-2-4-13(11)19-14/h1-9,16H,(H,17,18)/b8-6+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of [14C]-arachidonic acid conversion to 5-HETE by broken cell 5-lipoxygenase in vitro (guinea pig PMN)				Bioorg Med Chem Lett 1: 107-110 (1991) Article DOI: 10.1016/S0960-894X(00)80241-3 BindingDB Entry DOI: 10.7270/Q2DF6R3J
					More data for this Ligand-Target Pair