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SMILES: NC1CCCC(C1)C(=O)Nc1ccc2[nH]nc(Nc3cccc4ncccc34)c2c1

InChI Key: InChIKey=DNAOYMQGESKHSQ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50280098   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serine/threonine-protein kinase ULK1


(Homo sapiens (Human))		BDBM50280098
PNG
(CHEMBL4176003)
Show SMILES NC1CCCC(C1)C(=O)Nc1ccc2[nH]nc(Nc3cccc4ncccc34)c2c1
Show InChI InChI=1S/C23H24N6O/c24-15-5-1-4-14(12-15)23(30)26-16-9-10-21-18(13-16)22(29-28-21)27-20-8-2-7-19-17(20)6-3-11-25-19/h2-3,6-11,13-15H,1,4-5,12,24H2,(H,26,30)(H2,27,28,29)
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 40n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Inhibition of ATG13 binding to full-length ULK1 (unknown origin) expressed in HEK293T cells preincubated for 15 mins followed by human C-terminal FLA...

ACS Med Chem Lett 8: 1258-1263 (2017)


Article DOI: 10.1021/acsmedchemlett.7b00344
BindingDB Entry DOI: 10.7270/Q27S7R9H
More data for this
Ligand-Target Pair