BDBM50280119 2-[2-(1H-Imidazol-4-yl)-ethyl]-1-methyl-isothiourea; hydrobromide::CHEMBL554956
SMILES: CN=C(N)SCCc1cnc[nH]1
InChI Key: InChIKey=XNNCOKZTOXNCQG-UHFFFAOYSA-N
Data: 1 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Histamine H3 receptor (Rattus norvegicus (rat)) | BDBM50280119![]() (2-[2-(1H-Imidazol-4-yl)-ethyl]-1-methyl-isothioure...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | n/a | n/a | 15 | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description The compound was evaluated for agonistic effect on release of [3H]-histamine from rat brain cortical slices with L-[3H]-histidine at 0.3 microM | Bioorg Med Chem Lett 2: 1231-1234 (1992) Article DOI: 10.1016/S0960-894X(00)80219-X BindingDB Entry DOI: 10.7270/Q2J38SGF | |||||||||||
More data for this Ligand-Target Pair |