BDBM50280549 (Trans)-(R)-2,7-Dimethyl-1,3-dioxa-7-aza-spiro[4.4]nonane::CHEMBL167501

SMILES: C[C@@H]1OCC2(CCN(C)C2)O1

InChI Key: InChIKey=VZUXKQXNEMZLQZ-GVHYBUMESA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50280549   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50280549 ((Trans)-(R)-2,7-Dimethyl-1,3-dioxa-7-aza-spiro[4.4...) Show SMILES C[C@@H]1OCC2(CCN(C)C2)O1 Show InChI InChI=1S/C8H15NO2/c1-7-10-6-8(11-7)3-4-9(2)5-8/h7H,3-6H2,1-2H3/t7-,8?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	550	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro 100 nM cortex affinity to displace [3H]- -CD providing a measure of muscarinic m1 receptor agonist affinity				Bioorg Med Chem Lett 2: 815-820 (1992) Article DOI: 10.1016/S0960-894X(00)80537-5 BindingDB Entry DOI: 10.7270/Q23X8734
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50280549 ((Trans)-(R)-2,7-Dimethyl-1,3-dioxa-7-aza-spiro[4.4...) Show SMILES C[C@@H]1OCC2(CCN(C)C2)O1 Show InChI InChI=1S/C8H15NO2/c1-7-10-6-8(11-7)3-4-9(2)5-8/h7H,3-6H2,1-2H3/t7-,8?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	1.75E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro 100 nM cortex affinity to displace [3H]- -CD providing a measure of muscarinic m1 receptor agonist affinity				Bioorg Med Chem Lett 2: 815-820 (1992) Article DOI: 10.1016/S0960-894X(00)80537-5 BindingDB Entry DOI: 10.7270/Q23X8734
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50280549 ((Trans)-(R)-2,7-Dimethyl-1,3-dioxa-7-aza-spiro[4.4...) Show SMILES C[C@@H]1OCC2(CCN(C)C2)O1 Show InChI InChI=1S/C8H15NO2/c1-7-10-6-8(11-7)3-4-9(2)5-8/h7H,3-6H2,1-2H3/t7-,8?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro 100 nM cortex affinity to displace [3H]- -pirenzepine providing a measure of muscarinic m1 receptor antagonist affinity				Bioorg Med Chem Lett 2: 815-820 (1992) Article DOI: 10.1016/S0960-894X(00)80537-5 BindingDB Entry DOI: 10.7270/Q23X8734
					More data for this Ligand-Target Pair