BDBM50280962 7-Methoxy-4-phenyl-3H-naphtho[2,3-c]furan-1-one::CHEMBL291391

SMILES: COc1ccc2c(c3COC(=O)c3cc2c1)-c1ccccc1

InChI Key: InChIKey=IRXGJHWQZCQAGE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50280962   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Homo sapiens (Human))	BDBM50280962 (7-Methoxy-4-phenyl-3H-naphtho[2,3-c]furan-1-one | ...) Show SMILES COc1ccc2c(c3COC(=O)c3cc2c1)-c1ccccc1 Show InChI InChI=1S/C19H14O3/c1-21-14-7-8-15-13(9-14)10-16-17(11-22-19(16)20)18(15)12-5-3-2-4-6-12/h2-10H,11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytes				Bioorg Med Chem Lett 3: 2063-2066 (1993) Article DOI: 10.1016/S0960-894X(01)81016-7 BindingDB Entry DOI: 10.7270/Q2T43T1Z
					More data for this Ligand-Target Pair