BDBM50281797 4'-(2-Butyl-7-oxo-6,7-dihydro-imidazo[4,5-d]pyridazin-1-ylmethyl)-biphenyl-2-carboxylic acid::CHEMBL7396

SMILES: CCCCc1nc2cn[nH]c(=O)c2n1Cc1ccc(cc1)-c1ccccc1C(O)=O

InChI Key: InChIKey=ZNDMLFMZBUHBMB-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50281797   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II receptor (Homo sapiens (Human))	BDBM50281797 (4'-(2-Butyl-7-oxo-6,7-dihydro-imidazo[4,5-d]pyrida...) Show SMILES CCCCc1nc2cn[nH]c(=O)c2n1Cc1ccc(cc1)-c1ccccc1C(O)=O Show InChI InChI=1S/C23H22N4O3/c1-2-3-8-20-25-19-13-24-26-22(28)21(19)27(20)14-15-9-11-16(12-10-15)17-6-4-5-7-18(17)23(29)30/h4-7,9-13H,2-3,8,14H2,1H3,(H,26,28)(H,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	2.13E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of monoiodinated angiotensin II from guinea-pig adrenal gland angiotensin II receptor				Citation and Details BindingDB Entry DOI: 10.7270/Q2PG1TWM
					More data for this Ligand-Target Pair
Angiotensin II receptor (Homo sapiens (Human))	BDBM50281797 (4'-(2-Butyl-7-oxo-6,7-dihydro-imidazo[4,5-d]pyrida...) Show SMILES CCCCc1nc2cn[nH]c(=O)c2n1Cc1ccc(cc1)-c1ccccc1C(O)=O Show InChI InChI=1S/C23H22N4O3/c1-2-3-8-20-25-19-13-24-26-22(28)21(19)27(20)14-15-9-11-16(12-10-15)17-6-4-5-7-18(17)23(29)30/h4-7,9-13H,2-3,8,14H2,1H3,(H,26,28)(H,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
The M. S. University of Baroda Curated by ChEMBL					Assay Description Binding affinity to angiotensin AT1 receptor				Bioorg Med Chem 18: 8418-56 (2010) Article DOI: 10.1016/j.bmc.2010.10.043 BindingDB Entry DOI: 10.7270/Q2H70G3T
					More data for this Ligand-Target Pair