BDBM50282147 3-[3-(4-Chloro-phenylsulfamoyl)-propyl]-6-isopropyl-azulene-1-carboxylic acid::CHEMBL47658

SMILES: CC(C)c1ccc2c(CCCS(=O)(=O)Nc3ccc(Cl)cc3)cc(C(O)=O)c2cc1

InChI Key: InChIKey=VEMJQFPYGMUDGO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50282147   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thromboxane A2 receptor (RAT)	BDBM50282147 (3-[3-(4-Chloro-phenylsulfamoyl)-propyl]-6-isopropy...) Show SMILES CC(C)c1ccc2c(CCCS(=O)(=O)Nc3ccc(Cl)cc3)cc(C(O)=O)c2cc1 Show InChI InChI=1S/C23H24ClNO4S/c1-15(2)16-5-11-20-17(14-22(23(26)27)21(20)12-6-16)4-3-13-30(28,29)25-19-9-7-18(24)8-10-19/h5-12,14-15,25H,3-4,13H2,1-2H3,(H,26,27)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	9.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for antagonistic activity on isolated rat thoracic aorta (thromboxane A2 receptor) precontracted by U-46619 (3 x 10 e-8 M)				Bioorg Med Chem Lett 3: 1687-1692 (1993) Article DOI: 10.1016/S0960-894X(00)80043-8 BindingDB Entry DOI: 10.7270/Q2H70FQG
					More data for this Ligand-Target Pair