BDBM50282383 2-Ethyl-5,7-dimethyl-3-[2'-(2-oxo-2,3-dihydro-2lambda*4*-[1,2,3,5]oxathiadiazol-4-yl)-biphenyl-4-ylmethyl]-3H-imidazo[4,5-b]pyridine::CHEMBL344407

SMILES: CCc1nc2c(C)cc(C)nc2n1Cc1ccc(cc1)-c1ccccc1C1=NS(=O)ON1

InChI Key: InChIKey=NWZZJFYBFATYKU-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50282383   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II type 1a (AT-1a) receptor (RABBIT)	BDBM50282383 (2-Ethyl-5,7-dimethyl-3-[2'-(2-oxo-2,3-dihydro-2lam...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(cc1)-c1ccccc1C1=NS(=O)ON1 |t:30| Show InChI InChI=1S/C24H23N5O2S/c1-4-21-26-22-15(2)13-16(3)25-24(22)29(21)14-17-9-11-18(12-10-17)19-7-5-6-8-20(19)23-27-31-32(30)28-23/h5-13H,4,14H2,1-3H3,(H,27,28)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
The M. S. University of Baroda Curated by ChEMBL					Assay Description Binding affinity to angiotensin AT1 receptor in rabbit aortic rings				Bioorg Med Chem 18: 8418-56 (2010) Article DOI: 10.1016/j.bmc.2010.10.043 BindingDB Entry DOI: 10.7270/Q2H70G3T
					More data for this Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor (RABBIT)	BDBM50282383 (2-Ethyl-5,7-dimethyl-3-[2'-(2-oxo-2,3-dihydro-2lam...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(cc1)-c1ccccc1C1=NS(=O)ON1 |t:30| Show InChI InChI=1S/C24H23N5O2S/c1-4-21-26-22-15(2)13-16(3)25-24(22)29(21)14-17-9-11-18(12-10-17)19-7-5-6-8-20(19)23-27-31-32(30)28-23/h5-13H,4,14H2,1-3H3,(H,27,28)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of the specific binding ligand [125I]-Sar1,Ile8-AII from Angiotensin II receptor, type 1 in rabbit aorta membrane.				Bioorg Med Chem Lett 4: 41-44 (1994) Article DOI: 10.1016/S0960-894X(01)81119-7 BindingDB Entry DOI: 10.7270/Q2X92B6P
					More data for this Ligand-Target Pair