BDBM50282426 2-Butyl-3-[2'-(cyclopropanecarbonyl-sulfamoyl)-biphenyl-4-ylmethyl]-3H-imidazole-4-carboxylic acid::CHEMBL349856

SMILES: CCCCc1ncc(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)C1CC1

InChI Key: InChIKey=TWPGGMFJTGIQQP-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50282426   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II AT2 (RAT)	BDBM50282426 (2-Butyl-3-[2'-(cyclopropanecarbonyl-sulfamoyl)-bip...) Show SMILES CCCCc1ncc(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)C1CC1 Show InChI InChI=1S/C25H27N3O5S/c1-2-3-8-23-26-15-21(25(30)31)28(23)16-17-9-11-18(12-10-17)20-6-4-5-7-22(20)34(32,33)27-24(29)19-13-14-19/h4-7,9-12,15,19H,2-3,8,13-14,16H2,1H3,(H,27,29)(H,30,31)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory activity against angiotensin II (AT2) receptor to displace 125I-Sar,Ile8-AII in rat midbrain				Bioorg Med Chem Lett 4: 69-74 (1994) Article DOI: 10.1016/S0960-894X(01)81124-0 BindingDB Entry DOI: 10.7270/Q2NS0TVK
					More data for this Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor (RABBIT)	BDBM50282426 (2-Butyl-3-[2'-(cyclopropanecarbonyl-sulfamoyl)-bip...) Show SMILES CCCCc1ncc(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)C1CC1 Show InChI InChI=1S/C25H27N3O5S/c1-2-3-8-23-26-15-21(25(30)31)28(23)16-17-9-11-18(12-10-17)20-6-4-5-7-22(20)34(32,33)27-24(29)19-13-14-19/h4-7,9-12,15,19H,2-3,8,13-14,16H2,1H3,(H,27,29)(H,30,31)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	5.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory activity against Angiotensin II receptor, type 1 to displace 125I-Sar,Ile8-AII in rabbit aorta				Bioorg Med Chem Lett 4: 69-74 (1994) Article DOI: 10.1016/S0960-894X(01)81124-0 BindingDB Entry DOI: 10.7270/Q2NS0TVK
					More data for this Ligand-Target Pair