BDBM50282537 CHEMBL264739::{(S)-1-[1-(4-Benzyloxy-benzyl)-3,3-difluoro-3-isobutylcarbamoyl-2-oxo-propylcarbamoyl]-2-methyl-propyl}-carbamic acid benzyl ester

SMILES: CC(C)CNC(=O)C(F)(F)C(=O)C(Cc1ccc(OCc2ccccc2)cc1)NC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C

InChI Key: InChIKey=WQQBFTMCYZQIDP-ZSXSBBPPSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50282537   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 protease (Human immunodeficiency virus type 1)	BDBM50282537 (CHEMBL264739 | {(S)-1-[1-(4-Benzyloxy-benzyl)-3,3-...) Show SMILES CC(C)CNC(=O)C(F)(F)C(=O)C(Cc1ccc(OCc2ccccc2)cc1)NC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C Show InChI InChI=1S/C35H41F2N3O6/c1-23(2)20-38-33(43)35(36,37)31(41)29(19-25-15-17-28(18-16-25)45-21-26-11-7-5-8-12-26)39-32(42)30(24(3)4)40-34(44)46-22-27-13-9-6-10-14-27/h5-18,23-24,29-30H,19-22H2,1-4H3,(H,38,43)(H,39,42)(H,40,44)/t29?,30-/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity was determined against HIV-1 protease.				Bioorg Med Chem Lett 4: 1213-1218 (1994) Article DOI: 10.1016/S0960-894X(01)80332-2 BindingDB Entry DOI: 10.7270/Q24Q7TXS
					More data for this Ligand-Target Pair