BDBM50282612 6-(2-Butyl-1H-benzoimidazol-5-yl)-5-methyl-4,5-dihydro-2H-pyridazin-3-one::CHEMBL286470

SMILES: CCCCc1nc2ccc(cc2[nH]1)C1=NNC(=O)CC1C

InChI Key: InChIKey=URWCDYIFXDPUQK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50282612   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II type 1a (AT-1a) receptor (Bos taurus)	BDBM50282612 (6-(2-Butyl-1H-benzoimidazol-5-yl)-5-methyl-4,5-dih...) Show SMILES CCCCc1nc2ccc(cc2[nH]1)C1=NNC(=O)CC1C |t:15| Show InChI InChI=1S/C16H20N4O/c1-3-4-5-14-17-12-7-6-11(9-13(12)18-14)16-10(2)8-15(21)19-20-16/h6-7,9-10H,3-5,8H2,1-2H3,(H,17,18)(H,19,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Concentration required for 50% inhibition of binding against Angiotensin II receptor, type 1 in bovine adrenal cortex				Bioorg Med Chem Lett 4: 1297-1302 (1994) Article DOI: 10.1016/S0960-894X(01)80348-6 BindingDB Entry DOI: 10.7270/Q2G44QRD
					More data for this Ligand-Target Pair