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BDBM50282808 2-Butyl-6-((2S,3aR)-2-methyl-hexahydro-isoxazolo[2,3-a]pyridin-2-yl)-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-quinazolin-4-one::CHEMBL47873

SMILES: CCCCc1nc2ccc(cc2c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)[C@]1(C)C[C@H]2CCCCN2O1

InChI Key: InChIKey=NGHUUCYVFJXEDU-SFRLIIPVSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50282808   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Type-1 angiotensin II receptor


(Bos taurus)
BDBM50282808
PNG
(2-Butyl-6-((2S,3aR)-2-methyl-hexahydro-isoxazolo[2...)
Show SMILES CCCCc1nc2ccc(cc2c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)[C@]1(C)C[C@H]2CCCCN2O1
Show InChI InChI=1S/C34H37N7O2/c1-3-4-12-31-35-30-18-17-25(34(2)21-26-9-7-8-19-41(26)43-34)20-29(30)33(42)40(31)22-23-13-15-24(16-14-23)27-10-5-6-11-28(27)32-36-38-39-37-32/h5-6,10-11,13-18,20,26H,3-4,7-9,12,19,21-22H2,1-2H3,(H,36,37,38,39)/t26-,34+/m1/s1
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Article
n/an/a 47n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro Angiotensin II receptor antagonism in bovine adrenal cortex tissue.


Bioorg Med Chem Lett 4: 1703-1708 (1994)


Article DOI: 10.1016/S0960-894X(00)80365-0
BindingDB Entry DOI: 10.7270/Q2JS9QB3
More data for this
Ligand-Target Pair