BDBM50282819 2-Butyl-6-((2R,3aR)-2-ethyl-hexahydro-pyrrolo[1,2-b]isoxazol-2-yl)-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-quinazolin-4-one::CHEMBL44749

SMILES: CCCCc1nc2ccc(cc2c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)[C@@]1(CC)C[C@H]2CCCN2O1

InChI Key: InChIKey=ZPDBFUZSANKQIG-OOXUFLSTSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50282819   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II type 1a (AT-1a) receptor (Bos taurus)	BDBM50282819 (2-Butyl-6-((2R,3aR)-2-ethyl-hexahydro-pyrrolo[1,2-...) Show SMILES CCCCc1nc2ccc(cc2c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)[C@@]1(CC)C[C@H]2CCCN2O1 Show InChI InChI=1S/C34H37N7O2/c1-3-5-12-31-35-30-18-17-25(34(4-2)21-26-9-8-19-41(26)43-34)20-29(30)33(42)40(31)22-23-13-15-24(16-14-23)27-10-6-7-11-28(27)32-36-38-39-37-32/h6-7,10-11,13-18,20,26H,3-5,8-9,12,19,21-22H2,1-2H3,(H,36,37,38,39)/t26-,34-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro Angiotensin II receptor antagonism in bovine adrenal cortex tissue.				Bioorg Med Chem Lett 4: 1703-1708 (1994) Article DOI: 10.1016/S0960-894X(00)80365-0 BindingDB Entry DOI: 10.7270/Q2JS9QB3
					More data for this Ligand-Target Pair