BDBM50282872 2-(1-Cyclohexyl-1H-tetrazol-5-ylsulfanylmethyl)-1,1-dioxo-1,2-dihydro-1lambda*6*-benzo[d]isothiazol-3-one::CHEMBL53523

SMILES: O=C1N(CSc2nnnn2C2CCCCC2)S(=O)(=O)c2ccccc12

InChI Key: InChIKey=BCDWLRNOFVZHNG-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50282872   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukocyte elastase (Homo sapiens (Human))	BDBM50282872 (2-(1-Cyclohexyl-1H-tetrazol-5-ylsulfanylmethyl)-1,...) Show SMILES O=C1N(CSc2nnnn2C2CCCCC2)S(=O)(=O)c2ccccc12 Show InChI InChI=1S/C15H17N5O3S2/c21-14-12-8-4-5-9-13(12)25(22,23)19(14)10-24-15-16-17-18-20(15)11-6-2-1-3-7-11/h4-5,8-9,11H,1-3,6-7,10H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Potency of Inhibition of human leukocyte elastase (HLE) expressed as apparent binding constant				Bioorg Med Chem Lett 4: 1801-1806 (1994) Article DOI: 10.1016/S0960-894X(01)80374-7 BindingDB Entry DOI: 10.7270/Q25M65PP
					More data for this Ligand-Target Pair