BDBM50282877 4-Bromo-1,1-dioxo-2-(1-phenyl-1H-tetrazol-5-ylsulfanylmethyl)-1,2-dihydro-1lambda*6*-benzo[d]isothiazol-3-one::CHEMBL52118

SMILES: Brc1cccc2c1C(=O)N(CSc1nnnn1-c1ccccc1)S2(=O)=O

InChI Key: InChIKey=URQKIVBGGZPDRM-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50282877   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukocyte elastase (Homo sapiens (Human))	BDBM50282877 (4-Bromo-1,1-dioxo-2-(1-phenyl-1H-tetrazol-5-ylsulf...) Show SMILES Brc1cccc2c1C(=O)N(CSc1nnnn1-c1ccccc1)S2(=O)=O Show InChI InChI=1S/C15H10BrN5O3S2/c16-11-7-4-8-12-13(11)14(22)20(26(12,23)24)9-25-15-17-18-19-21(15)10-5-2-1-3-6-10/h1-8H,9H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Potency of Inhibition of human leukocyte elastase (HLE) expressed as apparent binding constant				Bioorg Med Chem Lett 4: 1801-1806 (1994) Article DOI: 10.1016/S0960-894X(01)80374-7 BindingDB Entry DOI: 10.7270/Q25M65PP
					More data for this Ligand-Target Pair