BDBM50282927 CHEMBL55476::[1-(3,5-Dimethyl-benzyloxymethyl)-2,2-diphenyl-ethyl]-methyl-amine

SMILES: CNC(COCc1cc(C)cc(C)c1)C(c1ccccc1)c1ccccc1

InChI Key: InChIKey=BVMNQSAYSSXTLM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50282927   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neurokinin 1 receptor (Homo sapiens (Human))	BDBM50282927 (CHEMBL55476 | [1-(3,5-Dimethyl-benzyloxymethyl)-2,...) Show SMILES CNC(COCc1cc(C)cc(C)c1)C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C25H29NO/c1-19-14-20(2)16-21(15-19)17-27-18-24(26-3)25(22-10-6-4-7-11-22)23-12-8-5-9-13-23/h4-16,24-26H,17-18H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	6.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity of the compound towards human Tachykinin receptor 1 expressed in CHO cells by the displacement of [125 I] substance P				Bioorg Med Chem Lett 4: 1903-1908 (1994) Article DOI: 10.1016/S0960-894X(01)80531-X BindingDB Entry DOI: 10.7270/Q2NK3DZ1
					More data for this Ligand-Target Pair