BDBM50283160 3-(2'-Hexanoylsulfamoyl-biphenyl-4-ylmethyl)-2-propyl-5-(4-pyridin-2-yl-piperazin-1-ylmethyl)-3H-imidazole-4-carboxylic acid::CHEMBL307321
SMILES: CCCCCC(=O)NS(=O)(=O)c1ccccc1-c1ccc(Cn2c(CCC)nc(CN3CCN(CC3)c3ccccn3)c2C(O)=O)cc1
InChI Key: InChIKey=FCVUJKNOEFEUJD-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Angiotensin II receptor (Homo sapiens (Human)) | BDBM50283160 (3-(2'-Hexanoylsulfamoyl-biphenyl-4-ylmethyl)-2-pro...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro binding affinity of compound against Angiotensin II receptor, type 1 | Bioorg Med Chem Lett 4: 2229-2234 (1994) Article DOI: 10.1016/S0960-894X(00)80076-1 BindingDB Entry DOI: 10.7270/Q2JQ110M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiotensin II receptor (Homo sapiens (Human)) | BDBM50283160 (3-(2'-Hexanoylsulfamoyl-biphenyl-4-ylmethyl)-2-pro...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro binding affinity of compound against angiotensin II AT-2 receptor | Bioorg Med Chem Lett 4: 2229-2234 (1994) Article DOI: 10.1016/S0960-894X(00)80076-1 BindingDB Entry DOI: 10.7270/Q2JQ110M | |||||||||||
More data for this Ligand-Target Pair |