BDBM50283163 2-Ethyl-5-(4-pyridin-2-yl-piperazin-1-ylmethyl)-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-imidazole-4-carboxylic acid::CHEMBL70389

SMILES: CCc1nc(CN2CCN(CC2)c2ccccn2)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1

InChI Key: InChIKey=RVXJRHYYTDDLLK-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50283163   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II receptor (Homo sapiens (Human))	BDBM50283163 (2-Ethyl-5-(4-pyridin-2-yl-piperazin-1-ylmethyl)-3-...) Show SMILES CCc1nc(CN2CCN(CC2)c2ccccn2)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C30H31N9O2/c1-2-26-32-25(20-37-15-17-38(18-16-37)27-9-5-6-14-31-27)28(30(40)41)39(26)19-21-10-12-22(13-11-21)23-7-3-4-8-24(23)29-33-35-36-34-29/h3-14H,2,15-20H2,1H3,(H,40,41)(H,33,34,35,36)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro binding affinity of compound against angiotensin II AT-2 receptor				Bioorg Med Chem Lett 4: 2229-2234 (1994) Article DOI: 10.1016/S0960-894X(00)80076-1 BindingDB Entry DOI: 10.7270/Q2JQ110M
					More data for this Ligand-Target Pair
Angiotensin II receptor (Homo sapiens (Human))	BDBM50283163 (2-Ethyl-5-(4-pyridin-2-yl-piperazin-1-ylmethyl)-3-...) Show SMILES CCc1nc(CN2CCN(CC2)c2ccccn2)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C30H31N9O2/c1-2-26-32-25(20-37-15-17-38(18-16-37)27-9-5-6-14-31-27)28(30(40)41)39(26)19-21-10-12-22(13-11-21)23-7-3-4-8-24(23)29-33-35-36-34-29/h3-14H,2,15-20H2,1H3,(H,40,41)(H,33,34,35,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro binding affinity of compound against Angiotensin II receptor, type 1				Bioorg Med Chem Lett 4: 2229-2234 (1994) Article DOI: 10.1016/S0960-894X(00)80076-1 BindingDB Entry DOI: 10.7270/Q2JQ110M
					More data for this Ligand-Target Pair