BDBM50283172 5-(4-Cyclopropanecarbonyl-piperazin-1-ylmethyl)-2-propyl-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-imidazole-4-carboxylic acid::CHEMBL309820

SMILES: CCCc1nc(CN2CCN(CC2)C(=O)C2CC2)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1

InChI Key: InChIKey=UADQBWZVELTJTR-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50283172   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II receptor (Homo sapiens (Human))	BDBM50283172 (5-(4-Cyclopropanecarbonyl-piperazin-1-ylmethyl)-2-...) Show SMILES CCCc1nc(CN2CCN(CC2)C(=O)C2CC2)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C30H34N8O3/c1-2-5-26-31-25(19-36-14-16-37(17-15-36)29(39)22-12-13-22)27(30(40)41)38(26)18-20-8-10-21(11-9-20)23-6-3-4-7-24(23)28-32-34-35-33-28/h3-4,6-11,22H,2,5,12-19H2,1H3,(H,40,41)(H,32,33,34,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro binding affinity of compound against Angiotensin II receptor, type 1				Bioorg Med Chem Lett 4: 2229-2234 (1994) Article DOI: 10.1016/S0960-894X(00)80076-1 BindingDB Entry DOI: 10.7270/Q2JQ110M
					More data for this Ligand-Target Pair
Angiotensin II receptor (Homo sapiens (Human))	BDBM50283172 (5-(4-Cyclopropanecarbonyl-piperazin-1-ylmethyl)-2-...) Show SMILES CCCc1nc(CN2CCN(CC2)C(=O)C2CC2)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C30H34N8O3/c1-2-5-26-31-25(19-36-14-16-37(17-15-36)29(39)22-12-13-22)27(30(40)41)38(26)18-20-8-10-21(11-9-20)23-6-3-4-7-24(23)28-32-34-35-33-28/h3-4,6-11,22H,2,5,12-19H2,1H3,(H,40,41)(H,32,33,34,35)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro binding affinity of compound against angiotensin II AT-2 receptor				Bioorg Med Chem Lett 4: 2229-2234 (1994) Article DOI: 10.1016/S0960-894X(00)80076-1 BindingDB Entry DOI: 10.7270/Q2JQ110M
					More data for this Ligand-Target Pair