BDBM50283329 1-Benzyl-4-(3-phenyl-prop-2-ynyloxymethyl)-piperidine::CHEMBL308185

SMILES: C(OCC1CCN(Cc2ccccc2)CC1)C#Cc1ccccc1

InChI Key: InChIKey=NBNYXJWRMQPRPT-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50283329   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50283329 (1-Benzyl-4-(3-phenyl-prop-2-ynyloxymethyl)-piperid...) Show SMILES C(OCC1CCN(Cc2ccccc2)CC1)C#Cc1ccccc1 Show InChI InChI=1S/C22H25NO/c1-3-8-20(9-4-1)12-7-17-24-19-22-13-15-23(16-14-22)18-21-10-5-2-6-11-21/h1-6,8-11,22H,13-19H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity towards sigma receptor using [3H]-(+)-SKF-10,047 as radioligand				Bioorg Med Chem Lett 4: 2347-2352 (1994) Article DOI: 10.1016/0960-894X(94)85038-0 BindingDB Entry DOI: 10.7270/Q2S75G8F
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (Homo sapiens (Human))	BDBM50283329 (1-Benzyl-4-(3-phenyl-prop-2-ynyloxymethyl)-piperid...) Show SMILES C(OCC1CCN(Cc2ccccc2)CC1)C#Cc1ccccc1 Show InChI InChI=1S/C22H25NO/c1-3-8-20(9-4-1)12-7-17-24-19-22-13-15-23(16-14-22)18-21-10-5-2-6-11-21/h1-6,8-11,22H,13-19H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	254	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity towards 5-HT2 receptor using [3H]ketanserin as radioligand				Bioorg Med Chem Lett 4: 2347-2352 (1994) Article DOI: 10.1016/0960-894X(94)85038-0 BindingDB Entry DOI: 10.7270/Q2S75G8F
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50283329 (1-Benzyl-4-(3-phenyl-prop-2-ynyloxymethyl)-piperid...) Show SMILES C(OCC1CCN(Cc2ccccc2)CC1)C#Cc1ccccc1 Show InChI InChI=1S/C22H25NO/c1-3-8-20(9-4-1)12-7-17-24-19-22-13-15-23(16-14-22)18-21-10-5-2-6-11-21/h1-6,8-11,22H,13-19H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity towards Dopamine receptor D2 using [3H]-spiperone as radioligand				Bioorg Med Chem Lett 4: 2347-2352 (1994) Article DOI: 10.1016/0960-894X(94)85038-0 BindingDB Entry DOI: 10.7270/Q2S75G8F
					More data for this Ligand-Target Pair