BDBM50283738 (S)-2-[(S)-5-((R)-2-Amino-3-mercapto-propionylamino)-2-(3,5-difluoro-benzyl)-pentanoylamino]-4-methylsulfanyl-butyric acid::CHEMBL92185

SMILES: CSCC[C@H](NC(=O)[C@@H](CCCNC(=O)[C@@H](N)CS)Cc1cc(F)cc(F)c1)C(O)=O

InChI Key: InChIKey=QAJIHSCJMHBCFI-JQFCIGGWSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50283738   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Geranylgeranyl transferase type I beta subunit/Protein Farnesyltransferase (PFT) (Homo sapiens (Human))	BDBM50283738 ((S)-2-[(S)-5-((R)-2-Amino-3-mercapto-propionylamin...) Show SMILES CSCC[C@H](NC(=O)[C@@H](CCCNC(=O)[C@@H](N)CS)Cc1cc(F)cc(F)c1)C(O)=O Show InChI InChI=1S/C20H29F2N3O4S2/c1-31-6-4-17(20(28)29)25-18(26)13(3-2-5-24-19(27)16(23)11-30)7-12-8-14(21)10-15(22)9-12/h8-10,13,16-17,30H,2-7,11,23H2,1H3,(H,24,27)(H,25,26)(H,28,29)/t13-,16-,17-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of farnesyl transferase				Bioorg Med Chem Lett 4: 2775-2780 (1994) Article DOI: 10.1016/S0960-894X(01)80593-X BindingDB Entry DOI: 10.7270/Q21J99Q0
					More data for this Ligand-Target Pair
Protein Farnesyltransferase (PFT) (Homo sapiens (Human))	BDBM50283738 ((S)-2-[(S)-5-((R)-2-Amino-3-mercapto-propionylamin...) Show SMILES CSCC[C@H](NC(=O)[C@@H](CCCNC(=O)[C@@H](N)CS)Cc1cc(F)cc(F)c1)C(O)=O Show InChI InChI=1S/C20H29F2N3O4S2/c1-31-6-4-17(20(28)29)25-18(26)13(3-2-5-24-19(27)16(23)11-30)7-12-8-14(21)10-15(22)9-12/h8-10,13,16-17,30H,2-7,11,23H2,1H3,(H,24,27)(H,25,26)(H,28,29)/t13-,16-,17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of farnesyl transferase				Bioorg Med Chem Lett 4: 2775-2780 (1994) Article DOI: 10.1016/S0960-894X(01)80593-X BindingDB Entry DOI: 10.7270/Q21J99Q0
					More data for this Ligand-Target Pair