BDBM50283740 (S)-2-[5-((R)-2-Amino-3-mercapto-propylamino)-2-benzyl-pentanoylamino]-4-methylsulfanyl-butyric acid::CHEMBL94412

SMILES: CSCC[C@H](NC(=O)[C@@H](CCCNC[C@@H](N)CS)Cc1ccccc1)C(O)=O

InChI Key: InChIKey=JVTJLYPWVINCJN-KSZLIROESA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50283740   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Geranylgeranyl transferase type I beta subunit/Protein Farnesyltransferase (PFT) (Homo sapiens (Human))	BDBM50283740 ((S)-2-[5-((R)-2-Amino-3-mercapto-propylamino)-2-be...) Show SMILES CSCC[C@H](NC(=O)[C@@H](CCCNC[C@@H](N)CS)Cc1ccccc1)C(O)=O Show InChI InChI=1S/C20H33N3O3S2/c1-28-11-9-18(20(25)26)23-19(24)16(12-15-6-3-2-4-7-15)8-5-10-22-13-17(21)14-27/h2-4,6-7,16-18,22,27H,5,8-14,21H2,1H3,(H,23,24)(H,25,26)/t16-,17+,18-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	5.95E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against geranylgeranyl transferase				Bioorg Med Chem Lett 4: 2775-2780 (1994) Article DOI: 10.1016/S0960-894X(01)80593-X BindingDB Entry DOI: 10.7270/Q21J99Q0
					More data for this Ligand-Target Pair
Protein Farnesyltransferase (PFT) (Homo sapiens (Human))	BDBM50283740 ((S)-2-[5-((R)-2-Amino-3-mercapto-propylamino)-2-be...) Show SMILES CSCC[C@H](NC(=O)[C@@H](CCCNC[C@@H](N)CS)Cc1ccccc1)C(O)=O Show InChI InChI=1S/C20H33N3O3S2/c1-28-11-9-18(20(25)26)23-19(24)16(12-15-6-3-2-4-7-15)8-5-10-22-13-17(21)14-27/h2-4,6-7,16-18,22,27H,5,8-14,21H2,1H3,(H,23,24)(H,25,26)/t16-,17+,18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of farnesyl transferase				Bioorg Med Chem Lett 4: 2775-2780 (1994) Article DOI: 10.1016/S0960-894X(01)80593-X BindingDB Entry DOI: 10.7270/Q21J99Q0
					More data for this Ligand-Target Pair