BDBM50283742 (S)-2-[(S)-5-((R)-2-Amino-3-mercapto-propionylamino)-2-benzyl-pentanoylamino]-4-methylsulfanyl-butyric acid::CHEMBL328075

SMILES: CSCC[C@H](NC(=O)[C@@H](CCCNC(=O)[C@@H](N)CS)Cc1ccccc1)C(O)=O

InChI Key: InChIKey=UMMFUJAKLTXUKT-ULQDDVLXSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50283742   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Farnesyltransferase (PFT) (Homo sapiens (Human))	BDBM50283742 ((S)-2-[(S)-5-((R)-2-Amino-3-mercapto-propionylamin...) Show SMILES CSCC[C@H](NC(=O)[C@@H](CCCNC(=O)[C@@H](N)CS)Cc1ccccc1)C(O)=O Show InChI InChI=1S/C20H31N3O4S2/c1-29-11-9-17(20(26)27)23-18(24)15(12-14-6-3-2-4-7-14)8-5-10-22-19(25)16(21)13-28/h2-4,6-7,15-17,28H,5,8-13,21H2,1H3,(H,22,25)(H,23,24)(H,26,27)/t15-,16-,17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of farnesyl transferase				Bioorg Med Chem Lett 4: 2775-2780 (1994) Article DOI: 10.1016/S0960-894X(01)80593-X BindingDB Entry DOI: 10.7270/Q21J99Q0
					More data for this Ligand-Target Pair
Geranylgeranyl transferase type I beta subunit/Protein Farnesyltransferase (PFT) (Homo sapiens (Human))	BDBM50283742 ((S)-2-[(S)-5-((R)-2-Amino-3-mercapto-propionylamin...) Show SMILES CSCC[C@H](NC(=O)[C@@H](CCCNC(=O)[C@@H](N)CS)Cc1ccccc1)C(O)=O Show InChI InChI=1S/C20H31N3O4S2/c1-29-11-9-17(20(26)27)23-18(24)15(12-14-6-3-2-4-7-14)8-5-10-22-19(25)16(21)13-28/h2-4,6-7,15-17,28H,5,8-13,21H2,1H3,(H,22,25)(H,23,24)(H,26,27)/t15-,16-,17-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.01E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against geranylgeranyl transferase				Bioorg Med Chem Lett 4: 2775-2780 (1994) Article DOI: 10.1016/S0960-894X(01)80593-X BindingDB Entry DOI: 10.7270/Q21J99Q0
					More data for this Ligand-Target Pair
Protein Farnesyltransferase (PFT) (Homo sapiens (Human))	BDBM50283742 ((S)-2-[(S)-5-((R)-2-Amino-3-mercapto-propionylamin...) Show SMILES CSCC[C@H](NC(=O)[C@@H](CCCNC(=O)[C@@H](N)CS)Cc1ccccc1)C(O)=O Show InChI InChI=1S/C20H31N3O4S2/c1-29-11-9-17(20(26)27)23-18(24)15(12-14-6-3-2-4-7-14)8-5-10-22-19(25)16(21)13-28/h2-4,6-7,15-17,28H,5,8-13,21H2,1H3,(H,22,25)(H,23,24)(H,26,27)/t15-,16-,17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against geranylgeranyl transferase				Bioorg Med Chem Lett 4: 2775-2780 (1994) Article DOI: 10.1016/S0960-894X(01)80593-X BindingDB Entry DOI: 10.7270/Q21J99Q0
					More data for this Ligand-Target Pair
Geranylgeranyl transferase type I beta subunit/Protein Farnesyltransferase (PFT) (Homo sapiens (Human))	BDBM50283742 ((S)-2-[(S)-5-((R)-2-Amino-3-mercapto-propionylamin...) Show SMILES CSCC[C@H](NC(=O)[C@@H](CCCNC(=O)[C@@H](N)CS)Cc1ccccc1)C(O)=O Show InChI InChI=1S/C20H31N3O4S2/c1-29-11-9-17(20(26)27)23-18(24)15(12-14-6-3-2-4-7-14)8-5-10-22-19(25)16(21)13-28/h2-4,6-7,15-17,28H,5,8-13,21H2,1H3,(H,22,25)(H,23,24)(H,26,27)/t15-,16-,17-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against geranylgeranyl transferase				Bioorg Med Chem Lett 4: 2775-2780 (1994) Article DOI: 10.1016/S0960-894X(01)80593-X BindingDB Entry DOI: 10.7270/Q21J99Q0
					More data for this Ligand-Target Pair