BDBM50283744 (S)-2-[5-((R)-2-Amino-3-mercapto-propylamino)-pentanoylamino]-4-methylsulfanyl-butyric acid::CHEMBL96905
SMILES: CSCC[C@H](NC(=O)CCCCNC[C@@H](N)CS)C(O)=O
InChI Key: InChIKey=CUDOQRFLUVNTOK-MNOVXSKESA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50283744 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Geranylgeranyl transferase type I beta subunit/Protein Farnesyltransferase (PFT)
(Homo sapiens (Human)) | BDBM50283744
((S)-2-[5-((R)-2-Amino-3-mercapto-propylamino)-pent...)Show InChI InChI=1S/C13H27N3O3S2/c1-21-7-5-11(13(18)19)16-12(17)4-2-3-6-15-8-10(14)9-20/h10-11,15,20H,2-9,14H2,1H3,(H,16,17)(H,18,19)/t10-,11+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibitory activity against geranylgeranyl transferase |
Bioorg Med Chem Lett 4: 2775-2780 (1994)
Article DOI: 10.1016/S0960-894X(01)80593-X BindingDB Entry DOI: 10.7270/Q21J99Q0 |
More data for this Ligand-Target Pair | |
Protein Farnesyltransferase (PFT)
(Homo sapiens (Human)) | BDBM50283744
((S)-2-[5-((R)-2-Amino-3-mercapto-propylamino)-pent...)Show InChI InChI=1S/C13H27N3O3S2/c1-21-7-5-11(13(18)19)16-12(17)4-2-3-6-15-8-10(14)9-20/h10-11,15,20H,2-9,14H2,1H3,(H,16,17)(H,18,19)/t10-,11+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 2.04E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of farnesyl transferase |
Bioorg Med Chem Lett 4: 2775-2780 (1994)
Article DOI: 10.1016/S0960-894X(01)80593-X BindingDB Entry DOI: 10.7270/Q21J99Q0 |
More data for this Ligand-Target Pair | |