Found 2 hits for monomerid = 50283747 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
(Homo sapiens (Human)) | BDBM50283747
((S)-2-[5-((R)-2-Amino-3-mercapto-propionylamino)-2...)Show SMILES CSCC[C@H](NC(=O)C(CCCNC(=O)[C@@H](N)CS)CC(c1ccccc1)c1ccccc1)C(O)=O Show InChI InChI=1S/C27H37N3O4S2/c1-36-16-14-24(27(33)34)30-25(31)21(13-8-15-29-26(32)23(28)18-35)17-22(19-9-4-2-5-10-19)20-11-6-3-7-12-20/h2-7,9-12,21-24,35H,8,13-18,28H2,1H3,(H,29,32)(H,30,31)(H,33,34)/t21?,23-,24-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibitory activity against geranylgeranyl transferase |
Bioorg Med Chem Lett 4: 2775-2780 (1994)
Article DOI: 10.1016/S0960-894X(01)80593-X BindingDB Entry DOI: 10.7270/Q21J99Q0 |
More data for this Ligand-Target Pair | |
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha
(Homo sapiens (Human)) | BDBM50283747
((S)-2-[5-((R)-2-Amino-3-mercapto-propionylamino)-2...)Show SMILES CSCC[C@H](NC(=O)C(CCCNC(=O)[C@@H](N)CS)CC(c1ccccc1)c1ccccc1)C(O)=O Show InChI InChI=1S/C27H37N3O4S2/c1-36-16-14-24(27(33)34)30-25(31)21(13-8-15-29-26(32)23(28)18-35)17-22(19-9-4-2-5-10-19)20-11-6-3-7-12-20/h2-7,9-12,21-24,35H,8,13-18,28H2,1H3,(H,29,32)(H,30,31)(H,33,34)/t21?,23-,24-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 1.86E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of farnesyl transferase |
Bioorg Med Chem Lett 4: 2775-2780 (1994)
Article DOI: 10.1016/S0960-894X(01)80593-X BindingDB Entry DOI: 10.7270/Q21J99Q0 |
More data for this Ligand-Target Pair | |