BDBM50283752 (S)-2-[(S)-5-((R)-2-Amino-3-mercapto-propionylamino)-2-thiophen-2-ylmethyl-pentanoylamino]-4-methylsulfanyl-butyric acid::CHEMBL316831

SMILES: CSCC[C@H](NC(=O)[C@@H](CCCNC(=O)[C@@H](N)CS)Cc1cccs1)C(O)=O

InChI Key: InChIKey=HMBVZGUDIZJMIK-QEJZJMRPSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50283752   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Geranylgeranyl transferase type I beta subunit/Protein Farnesyltransferase (PFT) (Homo sapiens (Human))	BDBM50283752 ((S)-2-[(S)-5-((R)-2-Amino-3-mercapto-propionylamin...) Show SMILES CSCC[C@H](NC(=O)[C@@H](CCCNC(=O)[C@@H](N)CS)Cc1cccs1)C(O)=O Show InChI InChI=1S/C18H29N3O4S3/c1-27-9-6-15(18(24)25)21-16(22)12(10-13-5-3-8-28-13)4-2-7-20-17(23)14(19)11-26/h3,5,8,12,14-15,26H,2,4,6-7,9-11,19H2,1H3,(H,20,23)(H,21,22)(H,24,25)/t12-,14-,15-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against geranylgeranyl transferase				Bioorg Med Chem Lett 4: 2775-2780 (1994) Article DOI: 10.1016/S0960-894X(01)80593-X BindingDB Entry DOI: 10.7270/Q21J99Q0
					More data for this Ligand-Target Pair
Protein Farnesyltransferase (PFT) (Homo sapiens (Human))	BDBM50283752 ((S)-2-[(S)-5-((R)-2-Amino-3-mercapto-propionylamin...) Show SMILES CSCC[C@H](NC(=O)[C@@H](CCCNC(=O)[C@@H](N)CS)Cc1cccs1)C(O)=O Show InChI InChI=1S/C18H29N3O4S3/c1-27-9-6-15(18(24)25)21-16(22)12(10-13-5-3-8-28-13)4-2-7-20-17(23)14(19)11-26/h3,5,8,12,14-15,26H,2,4,6-7,9-11,19H2,1H3,(H,20,23)(H,21,22)(H,24,25)/t12-,14-,15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of farnesyl transferase				Bioorg Med Chem Lett 4: 2775-2780 (1994) Article DOI: 10.1016/S0960-894X(01)80593-X BindingDB Entry DOI: 10.7270/Q21J99Q0
					More data for this Ligand-Target Pair