BDBM50283844 CHEMBL99289::N-tert-Butyl-2-[(3R,5S,7R)-5-(2-methoxy-phenyl)-2-oxo-7-phenyl-3-(3-m-tolyl-ureido)-azepan-1-yl]-acetamide
SMILES: COc1ccccc1[C@H]1C[C@@H](NC(=O)Nc2cccc(C)c2)C(=O)N(CC(=O)NC(C)(C)C)[C@H](C1)c1ccccc1
InChI Key: InChIKey=PKNBIEKWQLWZNJ-HNPKZYAISA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cholecystokinin receptor (Homo sapiens (Human)) | BDBM50283844 (CHEMBL99289 | N-tert-Butyl-2-[(3R,5S,7R)-5-(2-meth...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity against cholecystokinin-B (CCK-B) receptor in cortex of male hartley guinea pig. | Bioorg Med Chem Lett 4: 2877-2882 (1994) Article DOI: 10.1016/S0960-894X(01)80832-5 BindingDB Entry DOI: 10.7270/Q24B318F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholecystokinin A receptor (Cavia porcellus) | BDBM50283844 (CHEMBL99289 | N-tert-Butyl-2-[(3R,5S,7R)-5-(2-meth...) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 750 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity against cholecystokinin-A (CCK-A) receptor in pancreas of guinea pig. | Bioorg Med Chem Lett 4: 2877-2882 (1994) Article DOI: 10.1016/S0960-894X(01)80832-5 BindingDB Entry DOI: 10.7270/Q24B318F | |||||||||||
More data for this Ligand-Target Pair |