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SMILES: Cc1ccc(cc1)C(c1c[nH]c2ccc(cc12)C(=O)N\N=C\c1ccc(Cl)cc1Cl)c1c[nH]c2ccc(cc12)C(=O)N\N=C\c1ccc(Cl)cc1Cl

InChI Key: InChIKey=RURVWQYWCVVROV-ILMCGJENSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50284037   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Beta-glucuronidase


(Homo sapiens (Human))		BDBM50284037
PNG
(CHEMBL4171949)
Show SMILES Cc1ccc(cc1)C(c1c[nH]c2ccc(cc12)C(=O)N\N=C\c1ccc(Cl)cc1Cl)c1c[nH]c2ccc(cc12)C(=O)N\N=C\c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C40H28Cl4N6O2/c1-22-2-4-23(5-3-22)38(32-20-45-36-12-8-24(14-30(32)36)39(51)49-47-18-26-6-10-28(41)16-34(26)43)33-21-46-37-13-9-25(15-31(33)37)40(52)50-48-19-27-7-11-29(42)17-35(27)44/h2-21,38,45-46H,1H3,(H,49,51)(H,50,52)/b47-18+,48-19+
PDB

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PC cid
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UniChem

Similars
Article
PubMed
n/an/a 1.10E+3n/an/an/an/an/an/a



Imam Abdulrahman Bin Faisal University

Curated by ChEMBL


Assay Description
Inhibition of human beta-glucuronidase

Eur J Med Chem 143: 1757-1767 (2018)


Article DOI: 10.1016/j.ejmech.2017.10.071
BindingDB Entry DOI: 10.7270/Q23N25X1
More data for this
Ligand-Target Pair