BDBM50284168 (S)-2-((S)-2-{(S)-2-[((R)-2-Amino-3-mercapto-propionyl)-methyl-amino]-3-methyl-butyrylamino}-3-phenyl-propionylamino)-4-methylsulfanyl-butyric acid::CHEMBL169988

SMILES: CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C(C)C)N(C)C(=O)[C@@H](N)CS)C(O)=O

InChI Key: InChIKey=NIKLJFUBMPMVBM-VJANTYMQSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50284168   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50284168 ((S)-2-((S)-2-{(S)-2-[((R)-2-Amino-3-mercapto-propi...) Show SMILES CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C(C)C)N(C)C(=O)[C@@H](N)CS)C(O)=O Show InChI InChI=1S/C23H36N4O5S2/c1-14(2)19(27(3)22(30)16(24)13-33)21(29)26-18(12-15-8-6-5-7-9-15)20(28)25-17(23(31)32)10-11-34-4/h5-9,14,16-19,33H,10-13,24H2,1-4H3,(H,25,28)(H,26,29)(H,31,32)/t16-,17-,18-,19-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory concentration evaluated against P21ras Farnesyl transferase				Bioorg Med Chem Lett 4: 887-892 (1994) Article DOI: 10.1016/S0960-894X(01)80257-2 BindingDB Entry DOI: 10.7270/Q2N58MB6
					More data for this Ligand-Target Pair