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SMILES: CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)N(C)C(=O)[C@@H](NC(=O)[C@@H](N)CS)C(C)C)C(O)=O

InChI Key: InChIKey=PAAMBNNYTPBGMZ-VJANTYMQSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50284173   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha


(Rattus norvegicus-Rattus norvegicus (rat))		BDBM50284173
PNG
((S)-2-((S)-2-{[(S)-2-((R)-2-Amino-3-mercapto-propi...)
Show SMILES CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)N(C)C(=O)[C@@H](NC(=O)[C@@H](N)CS)C(C)C)C(O)=O
Show InChI InChI=1S/C23H36N4O5S2/c1-14(2)19(26-20(28)16(24)13-33)22(30)27(3)18(12-15-8-6-5-7-9-15)21(29)25-17(23(31)32)10-11-34-4/h5-9,14,16-19,33H,10-13,24H2,1-4H3,(H,25,29)(H,26,28)(H,31,32)/t16-,17-,18-,19-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
Article
n/an/a 360n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration evaluated against P21ras Farnesyl transferase

Bioorg Med Chem Lett 4: 887-892 (1994)


Article DOI: 10.1016/S0960-894X(01)80257-2
BindingDB Entry DOI: 10.7270/Q2N58MB6
More data for this
Ligand-Target Pair