BDBM50284209 1-Butyl-2,3-dimethyl-1,7-dihydro-5-oxa-1,7-diaza-indene-4,6-dione::CHEMBL174114

SMILES: CCCCn1c(C)c(C)c2c(O)oc(=O)nc12

InChI Key: InChIKey=WJHZPBQEGUWITM-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50284209   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukocyte elastase (Homo sapiens (Human))	BDBM50284209 (1-Butyl-2,3-dimethyl-1,7-dihydro-5-oxa-1,7-diaza-i...) Show SMILES CCCCn1c(C)c(C)c2c(O)oc(=O)nc12 Show InChI InChI=1S/C12H16N2O3/c1-4-5-6-14-8(3)7(2)9-10(14)13-12(16)17-11(9)15/h15H,4-6H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of human leukocyte elastase.				Bioorg Med Chem Lett 4: 949-954 (1994) Article DOI: 10.1016/S0960-894X(01)80270-5 BindingDB Entry DOI: 10.7270/Q27W6C4C
					More data for this Ligand-Target Pair
Alpha-chymotrypsin (Bos taurus (bovine))	BDBM50284209 (1-Butyl-2,3-dimethyl-1,7-dihydro-5-oxa-1,7-diaza-i...) Show SMILES CCCCn1c(C)c(C)c2c(O)oc(=O)nc12 Show InChI InChI=1S/C12H16N2O3/c1-4-5-6-14-8(3)7(2)9-10(14)13-12(16)17-11(9)15/h15H,4-6H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of porcine chymotrypsin.				Bioorg Med Chem Lett 4: 949-954 (1994) Article DOI: 10.1016/S0960-894X(01)80270-5 BindingDB Entry DOI: 10.7270/Q27W6C4C
					More data for this Ligand-Target Pair