BDBM50284212 9-Cyclohexyl-6-methoxy-1,9-dihydro-[1,3]oxazino[4,5-b]indole-2,4-dione::CHEMBL368710

SMILES: COc1ccc2n(C3CCCCC3)c3nc(=O)oc(O)c3c2c1

InChI Key: InChIKey=OGYCINXIPZRBQB-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50284212   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-chymotrypsin (Bos taurus (bovine))	BDBM50284212 (9-Cyclohexyl-6-methoxy-1,9-dihydro-[1,3]oxazino[4,...) Show SMILES COc1ccc2n(C3CCCCC3)c3nc(=O)oc(O)c3c2c1 Show InChI InChI=1S/C17H18N2O4/c1-22-11-7-8-13-12(9-11)14-15(18-17(21)23-16(14)20)19(13)10-5-3-2-4-6-10/h7-10,20H,2-6H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of porcine chymotrypsin.				Bioorg Med Chem Lett 4: 949-954 (1994) Article DOI: 10.1016/S0960-894X(01)80270-5 BindingDB Entry DOI: 10.7270/Q27W6C4C
					More data for this Ligand-Target Pair
Leukocyte elastase (Homo sapiens (Human))	BDBM50284212 (9-Cyclohexyl-6-methoxy-1,9-dihydro-[1,3]oxazino[4,...) Show SMILES COc1ccc2n(C3CCCCC3)c3nc(=O)oc(O)c3c2c1 Show InChI InChI=1S/C17H18N2O4/c1-22-11-7-8-13-12(9-11)14-15(18-17(21)23-16(14)20)19(13)10-5-3-2-4-6-10/h7-10,20H,2-6H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of human leukocyte elastase.				Bioorg Med Chem Lett 4: 949-954 (1994) Article DOI: 10.1016/S0960-894X(01)80270-5 BindingDB Entry DOI: 10.7270/Q27W6C4C
					More data for this Ligand-Target Pair