BDBM50284464 CHEMBL15788::[4-(2-Ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-2-propyl-phenoxy]-o-tolyl-acetic acid

SMILES: CCCc1cc(Cn2c(CC)nc3c(C)cc(C)nc23)ccc1OC(C(O)=O)c1ccccc1C

InChI Key: InChIKey=SZDCHUGPQOSQTF-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50284464   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II AT2 (RAT)	BDBM50284464 (CHEMBL15788 | [4-(2-Ethyl-5,7-dimethyl-imidazo[4,5...) Show SMILES CCCc1cc(Cn2c(CC)nc3c(C)cc(C)nc23)ccc1OC(C(O)=O)c1ccccc1C Show InChI InChI=1S/C29H33N3O3/c1-6-10-22-16-21(17-32-25(7-2)31-26-19(4)15-20(5)30-28(26)32)13-14-24(22)35-27(29(33)34)23-12-9-8-11-18(23)3/h8-9,11-16,27H,6-7,10,17H2,1-5H3,(H,33,34)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for its ability to displace the specific binding ligand [125I]-Sar 1,lle8-AlI from rat midbrain membrane (AT2 receptor)				Bioorg Med Chem Lett 5: 1151-1154 (1995) Article DOI: 10.1016/0960-894X(95)00185-V BindingDB Entry DOI: 10.7270/Q2J67GV9
					More data for this Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor (RABBIT)	BDBM50284464 (CHEMBL15788 | [4-(2-Ethyl-5,7-dimethyl-imidazo[4,5...) Show SMILES CCCc1cc(Cn2c(CC)nc3c(C)cc(C)nc23)ccc1OC(C(O)=O)c1ccccc1C Show InChI InChI=1S/C29H33N3O3/c1-6-10-22-16-21(17-32-25(7-2)31-26-19(4)15-20(5)30-28(26)32)13-14-24(22)35-27(29(33)34)23-12-9-8-11-18(23)3/h8-9,11-16,27H,6-7,10,17H2,1-5H3,(H,33,34)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for its ability to displace the specific binding ligand [125I]-Sar 1,lle8-AlI from rabbit aortic membrane (AT1 receptor)				Bioorg Med Chem Lett 5: 1151-1154 (1995) Article DOI: 10.1016/0960-894X(95)00185-V BindingDB Entry DOI: 10.7270/Q2J67GV9
					More data for this Ligand-Target Pair