BDBM50284649 4-Hydroxy-N-{3-[2'-(1-methyl-1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-4-oxo-3,4-dihydro-quinazolin-6-yl}-N-pentyl-benzamide::CHEMBL28464

SMILES: CCCCCN(C(=O)c1ccc(O)cc1)c1ccc2ncn(Cc3ccc(cc3)-c3ccccc3-c3nnnn3C)c(=O)c2c1

InChI Key: InChIKey=OURZJUVVAKFFMH-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50284649   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II type 1a (AT-1a) receptor (RABBIT)	BDBM50284649 (4-Hydroxy-N-{3-[2'-(1-methyl-1H-tetrazol-5-yl)-bip...) Show SMILES CCCCCN(C(=O)c1ccc(O)cc1)c1ccc2ncn(Cc3ccc(cc3)-c3ccccc3-c3nnnn3C)c(=O)c2c1 Show InChI InChI=1S/C35H33N7O3/c1-3-4-7-20-42(34(44)26-14-17-28(43)18-15-26)27-16-19-32-31(21-27)35(45)41(23-36-32)22-24-10-12-25(13-11-24)29-8-5-6-9-30(29)33-37-38-39-40(33)2/h5-6,8-19,21,23,43H,3-4,7,20,22H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against AT1 receptor in rabbit aorta				Bioorg Med Chem Lett 5: 1359-1364 (1995) Article DOI: 10.1016/0960-894X(95)00224-H BindingDB Entry DOI: 10.7270/Q2086589
					More data for this Ligand-Target Pair
Angiotensin II receptor (AT-1) type-1 (RAT)	BDBM50284649 (4-Hydroxy-N-{3-[2'-(1-methyl-1H-tetrazol-5-yl)-bip...) Show SMILES CCCCCN(C(=O)c1ccc(O)cc1)c1ccc2ncn(Cc3ccc(cc3)-c3ccccc3-c3nnnn3C)c(=O)c2c1 Show InChI InChI=1S/C35H33N7O3/c1-3-4-7-20-42(34(44)26-14-17-28(43)18-15-26)27-16-19-32-31(21-27)35(45)41(23-36-32)22-24-10-12-25(13-11-24)29-8-5-6-9-30(29)33-37-38-39-40(33)2/h5-6,8-19,21,23,43H,3-4,7,20,22H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against AT1 receptor in rat adrenal tissue				Bioorg Med Chem Lett 5: 1359-1364 (1995) Article DOI: 10.1016/0960-894X(95)00224-H BindingDB Entry DOI: 10.7270/Q2086589
					More data for this Ligand-Target Pair
Angiotensin II receptor (Homo sapiens (Human))	BDBM50284649 (4-Hydroxy-N-{3-[2'-(1-methyl-1H-tetrazol-5-yl)-bip...) Show SMILES CCCCCN(C(=O)c1ccc(O)cc1)c1ccc2ncn(Cc3ccc(cc3)-c3ccccc3-c3nnnn3C)c(=O)c2c1 Show InChI InChI=1S/C35H33N7O3/c1-3-4-7-20-42(34(44)26-14-17-28(43)18-15-26)27-16-19-32-31(21-27)35(45)41(23-36-32)22-24-10-12-25(13-11-24)29-8-5-6-9-30(29)33-37-38-39-40(33)2/h5-6,8-19,21,23,43H,3-4,7,20,22H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against AT1 receptor in human adrenal tissue				Bioorg Med Chem Lett 5: 1359-1364 (1995) Article DOI: 10.1016/0960-894X(95)00224-H BindingDB Entry DOI: 10.7270/Q2086589
					More data for this Ligand-Target Pair