BDBM50284828 CHEMBL39151::Sodium; 6-fluoro-3-methyl-2-(4-pyridin-3-yl-phenyl)-quinoline-4-carboxylate

SMILES: Cc1c(nc2ccc(F)cc2c1C([O-])=O)-c1ccc(cc1)-c1cccnc1

InChI Key: InChIKey=GKWOCDQQLIRDEU-UHFFFAOYSA-M

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50284828   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydroorotate dehydrogenase (Homo sapiens (Human))	BDBM50284828 (CHEMBL39151 | Sodium; 6-fluoro-3-methyl-2-(4-pyrid...) Show SMILES Cc1c(nc2ccc(F)cc2c1C([O-])=O)-c1ccc(cc1)-c1cccnc1 Show InChI InChI=1S/C22H15FN2O2/c1-13-20(22(26)27)18-11-17(23)8-9-19(18)25-21(13)15-6-4-14(5-7-15)16-3-2-10-24-12-16/h2-12H,1H3,(H,26,27)/p-1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition measurement of orotate formation from radiolabelled dihydroorotate, using partially purified DHODase isolated from human liver.				Bioorg Med Chem Lett 5: 1549-1554 (1995) Article DOI: 10.1016/0960-894X(95)00252-O BindingDB Entry DOI: 10.7270/Q29K4B55
					More data for this Ligand-Target Pair