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SMILES: OC(=O)c1cc(nc2sccc12)-c1ccc(cc1)-c1ccccc1

InChI Key: InChIKey=LBLUKZDJRQOAMW-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50284833   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dihydroorotate dehydrogenase (quinone), mitochondrial


(Homo sapiens (Human))		BDBM50284833
PNG
(6-Biphenyl-4-yl-thieno[2,3-b]pyridine-4-carboxylic...)
Show SMILES OC(=O)c1cc(nc2sccc12)-c1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C20H13NO2S/c22-20(23)17-12-18(21-19-16(17)10-11-24-19)15-8-6-14(7-9-15)13-4-2-1-3-5-13/h1-12H,(H,22,23)
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Article
 210n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition measurement of orotate formation from radiolabelled dihydroorotate, using partially purified DHODase isolated from human liver.

Bioorg Med Chem Lett 5: 1549-1554 (1995)


Article DOI: 10.1016/0960-894X(95)00252-O
BindingDB Entry DOI: 10.7270/Q29K4B55
More data for this
Ligand-Target Pair