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SMILES: Cn1cnc2c(cc(nc12)-c1ccc(cc1)-c1ccccc1)C(O)=O

InChI Key: InChIKey=ATVQTGSNSPKSCA-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50284847   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dihydroorotate dehydrogenase (quinone), mitochondrial


(Homo sapiens (Human))		BDBM50284847
PNG
(5-Biphenyl-4-yl-3-methyl-3H-imidazo[4,5-b]pyridine...)
Show SMILES Cn1cnc2c(cc(nc12)-c1ccc(cc1)-c1ccccc1)C(O)=O
Show InChI InChI=1S/C20H15N3O2/c1-23-12-21-18-16(20(24)25)11-17(22-19(18)23)15-9-7-14(8-10-15)13-5-3-2-4-6-13/h2-12H,1H3,(H,24,25)
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PC cid
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Article
>500n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition measurement of orotate formation from radiolabelled dihydroorotate, using partially purified DHODase isolated from human liver.

Bioorg Med Chem Lett 5: 1549-1554 (1995)


Article DOI: 10.1016/0960-894X(95)00252-O
BindingDB Entry DOI: 10.7270/Q29K4B55
More data for this
Ligand-Target Pair